research Understanding the biochemical properties of human hair keratins : self-assembly potential and cell response
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
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research Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy
EMT plays a key role in skin fibrosis and offers new therapy targets.
research Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology
Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.
research Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies
Genetics can help tailor treatments for male pattern hair loss, improving outcomes like stabilization or modest regrowth.
research miR-133a-3p and miR-145-5p co-promote goat hair follicle stem cell differentiation by regulating NANOG and SOX9 expression
miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.
research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Role of miRNAs in Sheep Hair Follicle Development
Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Deciphering the cellular landscape and genetic underpinnings of fiber diameter determined by dermal papilla cells in fine-wool sheep
Dermal papilla cells are key to fine wool growth in sheep.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research Androgenetic Alopecia
Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.
research Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing
Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
research Molecular mechanisms of viral oncogenesis in humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research Clinical perspectives on the age-related increase of immunosuppressive activity
Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
research New insights into the functions of Cox-2 in skin and esophageal malignancies
Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
research Valproic acid promotes human hair growth in in vitro culture model
Valproic acid may help hair grow and could be a safe treatment for hair loss.
research Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia
PRP therapy increases hair density for androgenetic alopecia.
research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation?
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
research Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells
Dengue virus can infect human hair follicle cells and may cause hair loss.
research TGFβ family mimetic peptide promotes proliferation of human hair follicle dermal papilla cells and hair growth in C57BL/6 mice
A peptide called DPS-1 helps human scalp cells grow and stimulates hair growth in mice.
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection
PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
research Erythroid Differentiation Regulator 1 as a Novel Biomarker for Hair Loss Disorders
Erdr1 could be a new marker for diagnosing hair loss.
research Androgenetic alopecia: Update on etiology
AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
research Melanocytes and Vitiligo (and Hair Graying)
Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
research 699 Effect of Prostaglandin D 2 on hair follicle growth and its impact on hair follicle stem/progenitor cells
Blocking Prostaglandin D₂ may help treat hair loss.
research Gut Microbiota and Autoimmune Alopecia Areata: Current Insights from the Literature
Gut microbiota changes might play a role in alopecia areata, and microbiome-targeted treatments show promise.
research Research advances of tissue-derived extracellular vesicles in cancers
Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
research Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway
A type of collagen helps hair grow by boosting cell growth and activating a specific hair growth pathway.