research A new way to restore tumour suppressor function
New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.
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research Pharmacological Application of Growth Factors: Basic and Clinical
Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.
research Thymosin β4 promotes angiogenesis, wound healing, and hair follicle development
Thymosin β4 helps heal wounds, grow hair, and improve blood vessel formation.
research Thrombospondin-1 Plays a Critical Role in the Induction of Hair Follicle Involution and Vascular Regression During the Catagen Phase
Thrombospondin-1 is crucial for hair follicle regression and reduced blood vessel growth during the catagen phase.
research Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Finding Parallels
Human stem cells can aid stroke recovery, research experiences boost students' career aspirations, minoxidil may reduce cancer spread, a molecule can slow tumor growth, a protein affects water flow in cells, magnesium behaves differently at tiny scales, and a new method detects slow-moving objects.
research ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1
ADM scaffolds help skin heal by promoting a healing-type immune response.
research Platelet-rich autoplazma effect on intestinal anastomosis regeneration in rabbits
PRP injections improve intestinal healing in rabbits with fewer complications than soaking.
research 1726: Risk Decrease of Intra-Operative Bleeding During TURP with the Uptake of Finasteride: Evaluation of VEGF and CD34
Finasteride reduces bleeding risk during prostate surgery.
research Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability
Compound 6 is a promising candidate for better wound healing.
research VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro
VEGF165 influences hair follicle cell growth and movement through VEGFR-2 activation.
research Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells
Hair follicle cells can create new blood vessels in the skin.
research Isoginkgetin, a natural biflavonoid from Ginkgo biloba, inhibits inflammatory response in endothelial cells via suppressing NF-κB activation
Isoginkgetin reduces inflammation in cells by blocking NF-κB activation.
research Rapid angiogenic hydrogel nanofiber scaffold promotes random flap regeneration and modulates inflammation
The hydrogel scaffold improved skin flap healing and reduced inflammation.
research Synthesis and biological screening of small molecule peptides based on the amino acid sequence of thymosin β4
Some synthesized peptides improved cell growth better than thymosin β4, VEGF, and minoxidil.
research Bioassay-guided isolation of two antiproliferative metabolites from Pterocarpus indicus Willd. against TGF-β-induced prostate stromal cells (WPMY-1) proliferation via PI3K/AKT signaling pathway
Compounds from Pterocarpus indicus may help treat benign prostatic hyperplasia by stopping cell growth.
research Exploring the role of two polypeptide nanofiber gels derived from RADA16-I self-assembly in accelerating burn wound healing
RG and RJ gels speed up burn wound healing better than other treatments.
research RAGE and Its Ligands in Melanoma
RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
research Presentation1.PPTX
Glypican-1 is important for hair follicle blood vessel growth and could be a target for treating hair loss.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research THE ROLE OF PLATELET-RICH PLASMA IN ANDROGENETIC ALOPECIA: A COMPREHENSIVE NARRATIVE REVIEW
PRP is a promising treatment for hair loss.
research Platelet-rich plasma accelerates skin wound healing by promoting re-epithelialization
Platelet-rich plasma speeds up skin wound healing.
research Smooth muscle cell expression of a constitutive active form of human Profilin1 accelerates cutaneous wound repair
Profilin1 speeds up wound healing.
research A functional role of S100A4/non-muscle myosin IIA axis for pro-tumorigenic vascular functions in glioblastoma
High S100A4 levels worsen glioblastoma by promoting blood vessel growth.
research Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis
research An off-the-shelf bioactive EV delivering cryogel orchestrating immunomodulatory reprogramming and angiogenesis for diabetic ulcer healing
BOOST is a promising, easy-to-use treatment for diabetic foot ulcers that improves healing by reducing inflammation and promoting blood vessel growth.
research Dermal papilla cells from human hair follicles secrete factors (e.g. VEGF) mitogenic for endothelial cells.
Dermal papilla cells help hair growth by releasing growth-promoting factors.
research EP-2270: Novel protective effect of prostaglandin for timely hair follicle regeneration from radiation injury
Prostaglandin helps regenerate hair follicles after radiation damage.
research 730 M2 macrophages promote wound induced hair neogenesis through the production of growth factors
M2 macrophages help hair regrowth in wounds by making growth factors.
research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.