![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/assets/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
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570-600 / 1000+ results research MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis
MYB30 and EIN3 work against each other to control root hair growth and phosphorus uptake in plants when phosphate is low.
research Thiopurines: Recent Topics and Their Role in the Treatment of Inflammatory Bowel Diseases
Thiopurines help treat IBD but require genetic testing to avoid side effects.
research Molecular insights into the formation of drug-polymer inclusion complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research Development of Fast Reverse Phase Liquid Chromatographic Method for Simultaneous Analysis of Betamethasone Dipropionate and Calcipotriol in Ointments and Bulk Drug
Researchers developed a quick and reliable method to test for betamethasone dipropionate and calcipotriol in ointments and drugs.
research CHEMICAL FORM OF THE IODINE PRESENT IN THE HAIR OF THE RAT
Iodine in rat hair is linked to hair growth.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
research Inositol hexaphosphate alleviates ototoxicity and age‐related hearing loss by preserving cochlear hair cells in mice
Inositol hexaphosphate helps protect hearing by preserving ear cells in mice.
research Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus In Vitro and In Vivo
Certain plant compounds can help prevent and treat a virus in pigs.
research Characterization of spironolactone and metabolites derivatized using Girard's reagent P using mass spectrometry and ion mobility spectrometry
Girard's reagent P improves detection of spironolactone and its metabolites.
research Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Sensitive Bromatometric Determination Of Finasteride In Pharmaceuticals Based On Complex-Formation Reactions
Two accurate methods were developed to measure finasteride in tablets.
research A method for the determination of minoxidil in hair-regrowth formulations by micellar electrokinetic capillary chromatography
A quick and simple method was created to identify minoxidil in hair-growth products using micellar electrokinetic capillary chromatography.
research 446 Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway
Finasteride helps female-pattern hair loss.
research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration
Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
research In vitro and in vivo study of dye diffusion into the human skin and hair follicles
Dyes can penetrate human skin and hair follicles up to 1.2 mm deep and the sebaceous gland can store dye; Indocyanine Green lotion was made for safe dyeing and monitoring.
research Use of Myoinositol in PCOS
Myoinositol effectively manages PCOS with fewer side effects than metformin.
research Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing
Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.
research ENRIQUECIMENTO AMBIENTAL ASSOCIADO A PROMOÇÃO DO BEM ESTAR PARA CAMUNDONGOS MANTIDOS EM BIOTÉRIOS
Environmental enrichment improves lab mice welfare and research outcomes.
research Tratamento da caspa e seborreia através da argiloterapia e óleos essenciais: revisão integrativa
Combining essential oils with clay therapy effectively treats dandruff and seborrhea.
research DOENÇA INTESTINAL INFLAMATÓRIA EM FELINOS: UMA REVISÃO DE LITERATURA
Early diagnosis and management are crucial for feline inflammatory bowel disease.
research ASPECTOS DA ESTRONGILOIDÍASE EM CÃES E O SEU IMPACTO NO ÂMBITO DA SAÚDE PÚBLICA
Dogs can transmit a parasite to humans, especially affecting those with weak immune systems, so early diagnosis and treatment are crucial.
research ABATE CLANDESTINO DE BOVINOS: RISCOS E CONSEQUÊNCIAS
Illegal cattle slaughter in Brazil poses health risks and violates laws.
research O VÍRUS DA GRIPE AVIÁRIA (H5N1): UMA REVISÃO DE LITERATURA
H5N1 avian flu poses risks to birds and humans, requiring strict biosecurity measures.
research LASERTERAPIA E SUAS APLICAÇÕES NO TRATAMENTO E REABILITAÇÃO DE PEQUENOS ANIMAIS COM OSTEOARTROSE
Laser therapy helps relieve pain and improve life quality in small animals with osteoarthritis.
research ATUALIZAÇÕES DA LEGISLAÇÃO SOBRE A RESPONSABILIDADE DO MÉDICO VETERINÁRIO NA PRESERVAÇÃO DO BEM-ESTAR ANIMAL E GARANTIA DA QUALIDADE DOS PRODUTOS DA INDÚSTRIA DE CARNES
Veterinarians are essential for ensuring animal welfare and safe meat products in Brazil.
research AVALIAÇÃO DA CRIPTOSPORIDIOSE EM CÃES E SUAS IMPLICAÇÕES NA SAÚDE ÚNICA
Cryptosporidiosis in dogs can spread to humans, so prevention is crucial.
research OCORRÊNCIA DA GIARDÍASE EM CÃES E A SUA RELEVÂNCIA PARA A SAÚDE PÚBLICA
Giardiasis in dogs poses a public health risk, requiring better diagnosis, treatment, and sanitation.
research Farmácia Azevedo Carvalho, Cabeceiras de Bastos
Pharmacists play a key role in health education and managing treatments for conditions like hair loss and smoking cessation.
research Use of home photobiomodulation in the rehabilitation of patients with disabled: systematic review
Home photobiomodulation therapy can improve life quality and mobility for disabled individuals.