3 citations
,
September 2021 in “International Journal of Molecular Sciences” Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
3 citations
,
January 2021 in “Andrology” Low androgen levels reduce nitric oxide production in rat penile cells.
January 2024 in “Reproductive toxicology” Hesperidin helps protect against testicular damage caused by finasteride.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The study identified key genes and pathways linked to hair disorders, aiding precision medicine.
October 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” 5-alpha reductase inhibitors do not increase hip fracture risk.
28 citations
,
November 2017 in “Molecular and cellular endocrinology” Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
22 citations
,
March 2003 in “Steroids” PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
18 citations
,
June 2021 in “Endocrinology” Anti-androgens might help reduce COVID-19 severity in men.
15 citations
,
May 2017 in “Journal of Cellular Biochemistry” The hairless protein is important for skin, hair, and may influence cancer development.
1 citations
,
January 2002 in “PubMed” PM-9, like finasteride, may help treat certain diseases by blocking a key enzyme.
Testosterone's health effects are complex and not definitively understood.
April 2018 in “The Journal of Urology” Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.
January 1999 in “Birkhäuser Basel eBooks” Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.
62 citations
,
January 2004 in “PubMed” 5alpha-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT, offering symptom relief and potential future uses.
3 citations
,
November 2024 in “Egyptian Journal of Medical Human Genetics” SGK1 is important in cancer growth and treatment resistance, and targeting it could improve therapies.
November 2024 in “Journal of Family Medicine and Primary Care” 5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.
Dutasteride did not change rat spermatogenesis or oxidative stress but needs more research.
April 2020 in “Archivos españoles de urología” Dutasteride does not seem to change rat spermatogenesis or oxidative stress.
198 citations
,
September 2007 in “Clinics in Dermatology” Radiofrequency devices effectively tighten skin without surgery.
106 citations
,
August 2024 in “Annals of Medicine and Surgery” AI in robotic surgery improves precision and safety but faces cost and ethical challenges.
100 citations
,
May 2006 in “American Journal Of Pathology” Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
70 citations
,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
57 citations
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December 2012 in “Molecules” Murraya koenigii extract and mahanimbicine significantly speed up wound healing in rats.
55 citations
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August 2024 in “Heliyon” Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
35 citations
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October 2011 in “Medicine and science in sports and exercise” Muscles can make their own androgens, which may help muscle growth.
26 citations
,
February 2021 in “FEBS Journal” Targeting regulatory T cells may help treat age-related diseases.
24 citations
,
July 2023 in “Journal of Functional Biomaterials” Bubble-based systems show promise for precise, targeted drug delivery and diagnosis, especially in cancer treatment.
11 citations
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November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
10 citations
,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
8 citations
,
September 2024 in “Food Science & Nutrition” β-Sitosterol may help prevent heart disease, cancer, and diabetes, but more human studies are needed.