research COVID‐19, androgens, and androgenic alopecia
COVID-19 may worsen with androgens; anti-androgen drugs could help.
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research The Osler Lecture 2012 'Pharmacology 2.0, medicines, drugs and human enhancement'
The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.
research Isolation and validation of antimalarial compounds from Phyllanthus emblica leaves for new antimalarial drug development
Phyllanthus emblica leaves show potential for developing new antimalarial drugs with low toxicity.
research Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review
Tripeptides help heal wounds and regenerate skin by speeding up tissue repair and reducing inflammation.
research From bedside to bench: regulation of host factors in SARS-CoV-2 infection
The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.
research Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Correlation Between Nongenomic Action of C19-Steroids and COVID-19 Severity
Low testosterone may increase COVID-19 severity in men.
research Chemotherapy-Induced Alopecia
Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
research A Review of U.S. Patents in the Field of Organic Process Development Published during July and August 2004
The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
research An appraisal of laboratory models of androgenetic alopecia: A systematic review
Better hair loss models needed for research.
research Translational research in the generation of therapeutic medicine for wound healing: a review
New therapies show promise for wound healing, but more research is needed for safe, affordable options.
research LncRNA MTC enhances the proliferation of Liaoning cashmere goat skin fibroblasts by modulating GSTM1-ASK1 interaction
LncRNA MTC boosts growth of goat skin cells, improving cashmere quality.
research Evaluating cepharanthine analogues as natural drugs against SARS-CoV-2
Cepharanthine and tetrandrine show promise as COVID-19 drugs.
research Functional stem-cell based tissue engineered vascular grafts for high-risk donor populations
Diabetic patients' stem cells make vascular grafts more prone to clots, but new methods may improve grafts.
research Research progress on mechanisms of skin aging and anti-aging strategies
Personalized anti-aging strategies are important, considering genetics and lifestyle.
research Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring
The hydrogel speeds up diabetic wound healing and reduces scarring.
research Association between SQSTM1 dysregulation and risk in alopecia areata: a Mendelian randomization study
SQSTM1 gene issues may increase the risk of alopecia areata.
research Causal Relationship and Potential Common Pathogenic Mechanisms Between Alopecia Areata and Related Cancer
Alopecia areata might help slow down certain cancers.
research Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ferroptosis-related biomarkers in alopecia areata through machine learning
Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.
research Hair Loss and Androgen’s Role in the Era of COVID-19
Androgens may worsen COVID-19 and hair loss could indicate the disease's severity.
research Reply to comment on: The Gabrin sign
Men with male pattern baldness may be more at risk for severe COVID-19, and anti-androgen treatments could offer protection.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
research Hair follicle differentiation and regulation.
Hair follicle growth and development are controlled by specific genes and molecular signals.
research Pregnancy and Skin
Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.
research Identification of Telogen Markers Underscores that Telogen Is Far from a Quiescent Hair Cycle Phase
Telogen is an active phase with important biological processes, not a resting phase.
research iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice
A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
research The role of vasoactive peptides in skin homeostasis—focus on adiponectin and the kallikrein-kinin system
Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.
research Basic concepts, current evidence, and future potential for gene therapy in managing cutaneous wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research Clinical Patterns of Hair Loss in Men
The document concludes that more research is needed to understand hair loss in men and to find new treatments.
research The Efficacy of Local Autologous Platelet-Rich Plasma Prepared by Single and Double Spin Methods in the Treatment of Chronic Ulcer
The single spin PRP method helps heal chronic ulcers effectively.