research An optimized force-triggered density gradient sedimentation method for isolation of pelage follicle dermal papilla cells from neonatal mouse skin
New method efficiently isolates hair growth cells from newborn mouse skin.
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900-930 / 1000+ results research Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening
The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
research Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia
A new microneedle treatment could effectively regrow hair in androgenic alopecia.
research Fusarium sp. Strain K-23 Alleviates Salt Stress in Arabidopsis thaliana Through its Root Hair Growth-Promoting Effect
Fusarium sp. strain K-23 helps Arabidopsis plants grow better in salty soil by promoting root hair growth.
research Ultraviolet‐induced red fluorescence in androgenetic alopecia—indicating alterations in microbial composition
Red fluorescence in AGA scalps is linked to different microbes.
research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
research Skin-Associated Cartilage Is a Distinct Type of Lipid-Filled Tissue
Lipocartilage is a new type of tissue that affects hair growth and cartilage regeneration.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating β-Defensin-2 Expression
Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.
research Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes
Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
research Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis
Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
research Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
research Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA
Altering SSAT affects fat metabolism and body fat in mice.
research Potential Use of Human Periapical Cyst-Mesenchymal Stem Cells (hPCy-MSCs) as a Novel Stem Cell Source for Regenerative Medicine Applications
Human periapical cyst stem cells could be a promising source for regenerative medicine.
research Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin
DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.
research Metabolites from Macroalgae and Its Applications in the Cosmetic Industry: A Circular Economy Approach
Macroalgae compounds offer sustainable, effective benefits for cosmetics.
research Dissolving microneedles: Applications and growing therapeutic potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Ethnodermatological use of medicinal plants in India: From ayurvedic formulations to clinical perspectives – A review
Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.
research Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation
Biotin may help treat inflammatory bowel disease by reducing inflammation and improving gut health.
research CD34 + cell–derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis
CD34+ cells help heal damaged limbs by promoting blood vessel growth.
research Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice
Low selenium levels can extend lifespan but worsen health issues.
research Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process
Nanoparticles can effectively treat diseases by modifying blood vessel growth.
research Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression
P311 helps skin stem cells become myofibroblast-like cells, aiding wound healing.
research Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration
Zebrafish need MYC and FGF to regenerate inner ear hair cells.
research Rp-HPLC Determination of Quercetin in a Novel D-α-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma
The new formulation greatly improved quercetin absorption in rats.
research A novel missense mutation in the mouse hairless gene causes irreversible hair loss: Genetic and molecular analyses of Hrm1Enu
A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
research Enhancing 1α-Hydroxylase Activity with the 25-Hydroxyvitamin D-1α-Hydroxylase Gene in Cultured Human Keratinocytes and Mouse Skin
Adding a specific gene to skin cells can help treat skin disorders like psoriasis.
research Bioactive Compounds, Antioxidant Properties, and Cosmetic Applications of Selected Cold-Pressed Plant Oils from Seeds
Cold-pressed plant oils have valuable natural antioxidants and skin care benefits.