January 2026 in “Medicina” JAK inhibitors show promise for treating various skin disorders effectively and safely.
June 2024 in “Neuromuscular Disorders” Baricitinib successfully treated myasthenia gravis and alopecia in a patient.
October 2023 in “International journal of rheumatic diseases” New treatments targeting the JAK signaling pathway, especially JAK inhibitors, show promise for alopecia areata.
March 2022 in “International Journal of Trichology” Erlotinib can cause unusual hair growth, like long eyelashes and facial hair.
80 citations
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June 2002 in “Molecular Biology of the Cell” Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
2 citations
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May 2023 in “Plants” Allium hookeri extract may help promote hair growth and protect cells from damage.
April 2026 in “Antibodies” The role of antibodies in alopecia is unclear, but JAK inhibitors show promise for treatment.
August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
160 citations
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June 2008 in “American Journal Of Pathology” EGFR signaling is crucial for skin and hair health, and targeting it could help treat skin diseases and cancer.
98 citations
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November 1999 in “Dermatology Online Journal” IGF-1 can boost hair growth by promoting cell growth and preventing cell death.
1 citations
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October 2025 in “Current Issues in Molecular Biology” Escin improves skin blood flow and health by enhancing blood vessel networks.
April 2026 in “Journal of Inflammation Research” Alopecia areata and atopic dermatitis share immune system issues, and treatments like JAK inhibitors can help both.
February 2026 in “International Journal of Molecular Sciences” Removing Lrig1-positive cells in mice leads to temporary loss of sebaceous glands.
November 2025 in “Frontiers in Pharmacology” Xiaozhi Yufa decoction may help treat hair loss by improving hair growth and reducing inflammation.
38 citations
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January 2011 in “PubMed” EGFR inhibitors often cause skin issues like acne and dryness, which can be managed with specific treatments.
17 citations
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October 2023 in “Molecules” Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.
Ritlecitinib helps reduce inflammation and promote hair regrowth in alopecia areata, especially in patchy-type cases.
Dacomitinib can cause nail and skin issues, but these can be managed without stopping the drug.
May 2023 in “Journal of managed care & specialty pharmacy” Alopecia areata causes hair loss and life quality issues; current treatments are often unsatisfactory, but new drugs like JAK inhibitors show promise.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
32 citations
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May 2023 in “Preprints.org” Skin pigmentation varies due to genetics, UV exposure, and medications, with treatments available but requiring medical advice.
17 citations
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May 2013 in “Journal of Investigative Dermatology” Mutations in β1 integrins cause embryonic death but have milder effects on skin.
August 2025 in “American Journal of Dermatopathology” Accurate diagnosis and personalized treatment are crucial in dermatopathology.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
13 citations
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March 2023 in “International Journal of Molecular Sciences” Lower Gas6 and sAxl levels are linked to hair loss in COVID-19 survivors.
13 citations
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September 2021 in “Current Issues in Molecular Biology” Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.
3 citations
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September 2025 in “Frontiers in Immunology” JAK inhibitors are effective for treating moderate-to-severe alopecia areata.
1 citations
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April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
October 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
6 citations
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February 2023 in “Journal of nanobiotechnology” The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.