research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
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390-420 / 1000+ results research Inhibition of steroid 5 alpha-reductase with finasteride: sleep-related erections, potency, and libido in healthy men
research Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production
A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
research Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research Structural basis for the catalysis and inhibition of human steroid 5α‐reductase 2
The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
research PLATELET-RICH PLASMA VS. MINOXIDIL IN ANDROGENETIC ALOPECIA: COMPARATIVE EFFECTIVENESS, SAFETY, AND PATIENT SATISFACTION – A SYSTEMATIC REVIEW
PRP may be more effective and satisfying for hair regrowth than minoxidil, with similar safety.
research Analysis of Skin Regeneration and Barrier-Improvement Efficacy of Polydeoxyribonucleotide Isolated from Panax Ginseng (C.A. Mey.) Adventitious Root
Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Scientific Opinion on the substantiation of a health claim related to spermidine and prolongation of the growing phase (anagen) of the hair cycle pursuant to Article 13(5) of Regulation (EC) No 1924/2006
Spermidine may help extend the growth phase of hair.
research Answer of Regenerative Therapy Not Hair Treatment Patients with Androgenetic Alopecia Approved for Hairmetrix® Technology - Case Report
Rigenera® effectively improves hair condition in Androgenetic Alopecia, and HairMetrix® tracks progress well.
research Successful rapid subcutaneous desensitization to anakinra in a case of delayed‐type hypersensitivity reaction
A woman with a drug allergy to anakinra was successfully desensitized, allowing her to continue treatment without allergic reactions.
research Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation
Finasteride may help improve certain brain function issues linked to dopamine.
research My Experiences in Using Autologous Human Hair Follicular Stem Cells (AMT) With Regenera Technology Combination With Platelet Rich Plasma (PRP) for Androgenetic Alopecia Treatments – in Both Male Pattern Hair Loss (MPHL)&Female Pattern Hair Loss (FPHL) in Asian Populations.
The combination of hair follicle stem cells and PRP shows promise for treating hair loss in Asian men and women.
research Inhibition of 5α-reductase in the rat prostate by Cimicifuga racemosa
Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.
research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*
Finasteride safely lowers DHT levels without affecting testosterone.
research Treatment of Psoriasis vulgaris with a New Retinoic Acid Derivative Ro 10-9359
The treatment cleared psoriasis in some patients but caused side effects in most.
research Safety Profile and Efficacy of Biosea® Revive Serum for Hair Growth Through In Vitro Assessment and Clinical Evaluation
Biosea® Revive Serum is safe and effective for improving hair growth and health.
research The Processed Radish Extract Melanogenesis in Humans and Induces Anti-Photoaging Effects in Ultraviolet B-Induced Hairless Mouse Model
Heated radish extract may help lighten skin and reduce aging signs.
research PLATELET-RICH PLASMA (PRP) IN MODERN DERMATOLOGY AND AESTHETIC MEDICINE: BIOLOGICAL MECHANISMS, CLINICAL APPLICATIONS, AND FUTURE DIRECTIONS
PRP helps with hair loss and acne scars but needs standardized preparation for consistent results.
research 52814 Minoxidil exerts skin rejuvenation effects in human androgenetic alopecia xenotransplants in vivo
Minoxidil helps hair regrowth and has anti-aging effects on hair follicles.
![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase
Compound 15a was effective in inhibiting 5α-reductase.
research 5 alpha-reductase inhibition by a new synthetic steroid (PM-9) in cultures of Penicillium crustosum.
PM-9, like finasteride, may help treat certain diseases by blocking a key enzyme.
research Nuevas áreas de conocimiento y la problemática documental: la prospectiva de la paz en la Universidad de Granada
ADSC therapy is promising for antiaging skin treatment.
research COMPARATIVE EFFECTIVENESS OF REGENERATIVE BIOLOGICS IN AESTHETIC DERMATOLOGY: A SYSTEMATIC REVIEW WITH QUANTITATIVE SYNTHESIS EVALUATING EXOSOMES, PRP AND STEM-CELL-DERIVED THERAPIES ON SKIN AND HAIR
Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
research COMPARATIVE EFFECTIVENESS OF REGENERATIVE BIOLOGICS IN AESTHETIC DERMATOLOGY: A SYSTEMATIC REVIEW WITH QUANTITATIVE SYNTHESIS EVALUATING EXOSOMES, PRP AND STEM-CELL-DERIVED THERAPIES ON SKIN AND HAIR
Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
research Crown-X: A Novel Menstrual Stem Cell-Based Therapy for Hair Regeneration in Male Pattern Baldness
Crown-X may effectively restore hair in male pattern baldness using menstrual stem cells.
research Antibacterials/corticosteroids/minoxidil
research Cosmetic Potency of Puerariae Radix in Dermal Fibroblasts
Puerariae Radix extract may be a promising cosmetic ingredient for skin health.
research Structural optimization of pep7, a small peptide extracted from epimorphin, for effective induction of hair follicle anagen
Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.
research Polynucleotides Versus Platelet-Rich Plasma for Androgenetic Alopecia: A Case Series
Both treatments improved hair quality and thickness equally, with mild side effects.