January 2022 in “Pastic and aesthetic research” PRP helps skin regeneration but needs standardized testing for consistent results.
11 citations
,
May 2023 in “Proceedings of the National Academy of Sciences” MicroRNA-205 helps hair regrow by making hair follicle stem cells less stiff.
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
The hydrogel speeds up wound healing by fighting bacteria and helping tissue regrow.
April 2026 in “Microsystems & Nanoengineering” HA-gel-dex hydrogels help heal wounds and regenerate tissue effectively.
9 citations
,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
September 2025 in “Journal of Investigative Dermatology” SLC3A2 is crucial for hair follicle stem cell function and hair growth.
January 2024 in “Journal of Health Study and Medicine” Platelet-rich plasma helps heal and repair tissues, especially in gynecology and obstetrics.
41 citations
,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
18 citations
,
July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
6 citations
,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
1 citations
,
November 2025 in “Stem Cell Research & Therapy” Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.
118 citations
,
January 2013 in “Biomaterials” Keratin from human hair shows promise for medical uses like wound healing and tissue engineering.
18 citations
,
October 2022 in “Biomedicines” Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
10 citations
,
June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
14 citations
,
May 2017 in “European journal of dermatology/EJD. European journal of dermatology” Skin stem cells can help treat many skin diseases without invasive procedures.
143 citations
,
May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
1 citations
,
January 2023 in “In vivo/In Vivo” Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.
June 2026 in “Research Square” The study highlights the crucial role of THBS4 in hair regeneration by modulating the mechanical properties of the dermal niche, which reduces matrix stiffness and enhances interactions between the epidermis and dermis. This process activates hair follicle stem cells (HFSCs) and accelerates the transition from the telogen to anagen phase, promoting hair growth. THBS4 upregulation in dermal fibroblasts activates signaling pathways involving ITGB1, EGR1, and HMGCR, facilitating HFSC proliferation. Experiments with mice and organoids showed that THBS4 treatment significantly enhances hair regeneration, suggesting its potential as a therapeutic target for hair loss treatments. Further research is needed to explore the detailed mechanisms of THBS4 in extracellular matrix assembly and metabolic reprogramming.
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
31 citations
,
July 2022 in “Advanced healthcare materials/Advanced Healthcare Materials” A drug-free microneedle patch significantly promotes hair growth and prevents infections.
76 citations
,
December 2018 in “Aesthetic Plastic Surgery” Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.
37 citations
,
February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
30 citations
,
November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
11 citations
,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
January 2026 in “Regenerative Biomaterials” Strontium and cerium are most effective for tissue repair.
September 2025 in “Frontiers in Cell and Developmental Biology” TCM-derived nanovesicles show promise for wound healing and skin regeneration but need more research.
February 2023 in “Materials Express” Pine pollen extract helps wounds heal faster due to its antioxidant and anti-inflammatory effects.
330 citations
,
December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
140 citations
,
August 2011 in “Biomaterials” Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.