research Pooled safety and tolerability data from four placebo-controlled teriflunomide studies and extensions
Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.
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research Uncovering the complex relationship between balding, testosterone and skin cancers in men
Men with baldness are more prone to skin cancers on the scalp due to sun exposure, not testosterone.
research Spontaneous cutaneous adverse drug reaction reports—An analysis of a 10‐year dataset in Singapore
In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
research Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review
Caffeine improves hair growth, thickness, and reduces shedding.
research Transcriptome Profiling of Human Follicle Dermal Papilla Cells in response to Porphyra-334 Treatment by RNA-Seq
Porphyra-334 may help reduce wrinkles and promote hair growth.
research Moving Beyond Boundaries: Utilization of Longitudinal Exposure–Response Model for Bounded Outcome Score to Inform Decision Making in the Accelerated Drug Development Paradigm
A 50 mg daily dose of ritlecitinib is effective for alopecia areata, with temporary treatment breaks up to 6 weeks not affecting results.
research Recent therapeutic developments for acne
New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
research Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial
Cepharanthine is safe but not effective in significantly reducing COVID-19 recovery time.
research A Phase 1 Study to Investigate the Effects of Cortexolone 17α‐Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
Clascoterone is safe for the heart, even at high doses.
research Structural studies of two solid steroid compounds
Androsterone and finasteride have different solid forms, with new findings correcting previous errors and identifying a new form.
research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
research The efficacy of scalp cooling in patients receiving chemotherapy for primary gynecologic cancers: a randomized controlled trial
Scalp cooling reduces hair loss and improves quality of life during chemotherapy.
research Association between SQSTM1 dysregulation and risk in alopecia areata: a Mendelian randomization study
SQSTM1 gene issues may increase the risk of alopecia areata.
research Rationale and Design of a Novel, Phase 3, External and Synthetic Placebo-Controlled Clinical Trial of Ritlecitinib 50 mg and 100 mg for Alopecia Areata
Ritlecitinib is being tested for effectiveness and safety in treating severe alopecia areata.
research Oral Spermidine Supplementation Prolongs Hair Follicle Anagen Phase with Sustained Effects: A Randomized, Double-Blind, Placebo-Controlled Trial
Spermidine supplements can help extend the hair growth phase and may be useful for treating hair loss.
research Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program
Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.
research Cutaneous Adverse Drug Reactions to Antibiotics: How Much is the Extent of the Problem?
Antibiotics often cause skin reactions, making them a major health concern.
research Follikelhormone
Follicle Stimulating Hormone is important for fertility.
research Using risk analysis to guide changes to compounding formulae
Risk analysis is important for safely adjusting pharmaceutical formulas while maintaining their quality and effectiveness.
research Green and Emerging Microextraction Strategies for Bioanalytical Determination of Hormones: Trends, Challenges, and Applications
Microextraction techniques improve hormone testing while being environmentally friendly.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Suspected adverse reactions to medications and food supplements containing Serenoa repens: A worldwide analysis of pharmacovigilance and phytovigilance spontaneous reports
Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.
research Re‐Innovation in Clinical Trial Designs Based on Precision Therapy
Clinical trials should use innovative designs and biomarkers to improve precision therapy and patient outcomes.
research Histopathological Evidence of Occipital Involvement in Male Androgenetic Alopecia
Advanced male pattern baldness affects the back of the scalp, reducing hair follicles.
research Formulation and Evaluation of Herbal Based Hair Mask
Henna is a safer, natural hair dye but needs more research and standardization.
research Formulation and Evaluation of Herbal Based Hair Mask
Henna is a safer alternative to synthetic hair dyes but has limited color options.
research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.
research Novel delivery strategy: finasteride-loaded solid lipid nanoparticles for improved androgenetic alopecia therapy
The new delivery method for finasteride using nanoparticles may improve hair growth without skin issues.
research Microalgal Biofactories: Sustainable Solutions for Nutrition and Cosmetics
Microalgae can sustainably improve nutrition and cosmetics with their diverse beneficial compounds.
research A Systematic Scoping Review and Conceptual Analysis of New-Onset Fibromyalgia Manifestations After Non-Hospitalized COVID-19: Empirics, Definitions, Methodologies, Pathophysiology, Mapping of Literature, and Knowledge Gaps
New-onset fibromyalgia after COVID-19 is poorly understood and needs more research.