March 2026 in “Calcified Tissue International” The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
15 citations
,
February 2021 in “Scientific Reports” RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
January 2024 in “Dermatologic Therapy” PRP therapy with specific growth factors improves hair density and thickness in androgenic alopecia.
January 2013 in “Faculty of Health; Institute of Health and Biomedical Innovation” Four genetic risk areas related to male-pattern baldness were identified, with WNT signaling playing a role in its development.
53 citations
,
June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
3 citations
,
May 2023 in “Precision clinical medicine” Researchers found four genes that could help diagnose severe alopecia areata early.
July 2025 in “Journal of Investigative Dermatology” Nelfb is essential for dermal fat development and survival.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” PRP shows promise for improving hair growth in early to moderate hair loss but needs standardized methods for consistent results.
1 citations
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August 2023 in “Journal of Dentomaxillofacial Science” Freeze-dried platelet-rich plasma boosts bone growth in gum treatment.
CRISPR gene editing reduces harmful molecules in cells from Emery–Dreifuss Muscular Dystrophy patients.
November 2025 in “Figshare” SQSTM1 is linked to increased risk of alopecia areata.
42 citations
,
December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
21 citations
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January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
Targeting CXXC5 and GSK-3β may help treat male pattern baldness.
January 2021 in “Medical Research Archives” Genetically modified rats help reveal how vitamin D affects bone and skin health.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MPZL3 protein helps keep sebaceous gland size and cell growth in check.
10 citations
,
January 2010 in “Veterinary pathology” A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.
27 citations
,
April 2008 in “Journal of Biological Chemistry” HMG-CoA reductase is crucial for skin wound healing by regulating keratinocyte growth and blood vessel formation.
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
12 citations
,
May 2003 in “Journal of dermatological science” Hsc70 protein may influence hair growth by responding to androgens.
September 2025 in “Journal of Maxillofacial and Oral Surgery” Combining PRP with CGF is more effective for hair regrowth in androgenetic alopecia than PRP alone.
February 2025 in “International Journal of Biological Macromolecules” The hydrogel effectively treats hair loss using light to release nitric oxide.
April 2026 in “Tissue Engineering and Regenerative Medicine”
72 citations
,
November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
September 2019 in “Journal of Investigative Dermatology” Specialized ribosomes affect aging in human skin cells.
19 citations
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August 2008 in “Journal of The European Academy of Dermatology and Venereology” Bald areas have lower cell growth, more DNA damage, and increased cell death.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
November 2023 in “Benha Journal of Applied Sciences” Males with male pattern baldness have higher blood galectin-3 levels.
7 citations
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August 2020 in “Journal of The American Academy of Dermatology” The document sets guidelines to standardize reporting of PRP clinical trials for better reproducibility and comparability.