research Lucio Phenomenon: Sequelae of Neglected Leprosy
Early diagnosis of leprosy is crucial to prevent disabilities and spread, even in non-endemic areas.
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research Drug Eruptions
Any medication can cause skin reactions, some due to allergies and others due to dosage or genetic factors.
research Circulating sex hormone binding globulin levels are modified with intensive lifestyle intervention, but their changes did not independently predict diabetes risk in the Diabetes Prevention Program
Changes in SHBG levels don't predict diabetes risk reduction.
research A case report of a novel, integrative approach to Hashimoto’s thyroiditis with unexpected results
A 23-year-old woman with Hashimoto’s thyroiditis improved significantly after a 15-month integrative treatment plan.
research Effect of Eurycoma longifolia Extract on Testosterone Synthesis in TM3 Leydig Cells under Oxidative Stress
Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.
research Allergic contact dermatitis from glycerin in a moisturizing cream
Glycerin in hand cream can cause allergic skin reactions.
research The coudability sign of alopecia areata: the real story
The document concludes that anticonvulsants like phenytoin may cause skin reactions by affecting tryptophan metabolism and suggests researching vitamin levels in patients with drug reactions.
research Female pattern hair loss
FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.
research A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism
Spironolactone plus finasteride reduces hirsutism more effectively.
research Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for the Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays
The new LC-MS/MS method is more accurate and reliable than traditional immunoassays for measuring steroids in serum.
research Effect of Lifestyle Modifications on Reproductive Function among Infertile Obese Women with Polycystic Ovarian Syndrome
Lifestyle changes improve reproductive function and hormonal balance in obese women with PCOS.
research Effects of multiple plasma donation on donors’ biochemical parameters
Multiple plasma donations do not change donors' biochemical parameters.
research Minoxidil-Induced Stevens-Johnson Syndrome
Minoxidil can cause severe skin reactions like Stevens-Johnson syndrome in rare cases.
research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
research Hirsutism: diagnosis and treatment
The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
research Protective effects of melatonin against metabolic and reproductive disturbances in polycystic ovary syndrome in rats
Melatonin may help treat PCOS symptoms in rats.
research Effects of Oral Finasteride on Erectile Function in a Rat Model
Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
research The role of vitamin E in the management of polycystic ovarian syndrome
Vitamin E helps reduce PCOS symptoms and improves hormonal balance.
research Influence of TRPV3 mutation on hair growth cycle in mice
The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
research Management of Hirsutism
Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
research Comparison of high-dose finasteride (5 mg/day) versus low-dose finasteride (2.5 mg/day) in the treatment of hirsutism
Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
research Finasteride in the treatment of hirsutism: new therapeutic perspectives
Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
research Effect of finasteride in idiopathic hirsutism
Finasteride significantly reduces hair growth in women with idiopathic hirsutism.
research Major depletion of SOX2+ stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling
The pituitary gland functions normally even after losing most SOX2+ stem cells.
research Expert consensus on the management of telogen effluvium in India
Indian dermatologists recommend treating common hair loss with a balanced diet, stress reduction, mild shampoos, and sometimes minoxidil and supplements.
research Rapid Blood Pressure Control With Minoxidil
Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.
research Evaluation of the effect of injection of dutasteride as mesotherapeutic tool in treatment of androgenetic alopecia in males
Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.
research 5-Alpha-Reductase Inhibitors and Combination Therapy
Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
research Efficacy of platelet-rich plasma in androgenetic alopecia patients
PRP therapy safely improves hair growth in people with hair loss.
research Anti-Müllerian hormone gene polymorphism is associated with androgen levels in Chinese polycystic ovary syndrome patients with insulin resistance
Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.