research L'idea di fenomeno fra Kant ed Husserl
Increased Wnt signaling causes hair graying by depleting melanocyte stem cells in aged mice.
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research Life of the B10 Mouse: A View from the Hair Follicles and Tissue Stem Cells
Mice skin matures by day 200, leading to aging signs like curved hair follicles and white hairs due to changes in skin stem cells.
research Epidemiology of skin cancer in the mature patient
Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.
research Hair Graying Regulators Beyond Hair Follicle
Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
research Ageing skin, part 1: normal ageing
As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
research Inducible cre-mediated N-ras activation and PTEN inactivation in transgenic mouse melanocytes requires keratinocyte hyperplasia to elicit a melanocyte pathology
Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.
research Perifollicular Melanocyte Regeneration in Bullous Pemphigoid
Melanocytes can regenerate around hair follicles in bullous pemphigoid, especially in patients with darker skin.
research CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties
CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
research Preservation of melanoblasts of white hair follicles of segmental vitiligo lesions: A preliminary study
White hair follicles in vitiligo have fewer and less functional melanocytes.
research Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes
Hair follicle stem cells can become melanocytes to help treat skin depigmentation.
research Observation of cultured amelanotic melanocytes from hair follicles by atomic force microscopy
Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.
research 1233 Exploring the role of melanocyte subpopulations in vitiligo
A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.
research ERYTHROMELANOSIS FOLLICULARIS FACIEI ET COLLI
Three Iranian men had reddish-brown facial pigmentation with no effective treatment.
research Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment
The technique can isolate cells to help treat skin pigmentation issues.
research Aging in the sebaceous gland
Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
research Melanogenesis is coupled to murine anagen: Toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth
Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
research Hair(y) Matters in Melanoma Biology
The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
research Clinical Snippets
Melanoma risk tools need improvement, a gene mutation causes a hair disorder that might be treated by managing cell stress, a potential therapy for a skin-ear disorder involves blocking cell channels, skin wrinkling may indicate lung aging regardless of smoking, and oxidative stress might contribute to common baldness.
research Age-induced hair greying - the multiple effects of oxidative stress
Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
research Keratinocytes regulate the function of melanocytes
Keratinocytes control how melanocytes work.
research Synergy of understanding dermatologic disease and epidermal biology
Advancements in skin and hair biology improve dermatology care and cosmetic treatments.
research In vitro Differentiation of Melanocyte Stem Cells Derived from Vitiligo Patients into Functional Melanocytes
Melanocyte stem cells from non-affected skin in vitiligo patients can become functional melanocytes for potential therapy.
research Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis
More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
research From neural crest cells to melanocytes: cellular plasticity during development and beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Clinical Snippets
Melanoma risk tools need improvement, certain gene mutations cause skin diseases and could be treated by targeting those mutations, skin wrinkling may relate to lung aging due to genetic factors, and oxidative stress affects hair loss but can be reduced in low oxygen.
research Herbal insights into melanin synthesis: Enhancing hair health naturally
Melanin is important for hair color, health, and UV protection.
research Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits
Exosomal miR-222-3p reduces melanin production in rabbits by targeting the SOX10 gene.
research Characterization and Localization of Side Population Cells in Mouse Skin
Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.