research Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury
High-dose radiation speeds up aging in skin stem cells.
Search
for
Sort by
Research
30 / 1000+ results research 685 Modelling intrinsic and extrinsic cellular senescence in vitro with complex bioengineered human skin constructs
Bioengineered skin models aging well, useful for studying aging and testing treatments.
research Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
Targeting cellular senescence may improve skin aging and disorders.
research Imbalanced redox dynamics induce fibroblast senescence leading to impaired stem cell pools and skin aging
Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
research 487 Exploring ribosomal RNA modifications and corresponding snoRNAs in human skin cell senescence
Understanding snoRNA regulation may help slow skin aging.
research Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage
Honokiol helps protect skin from damage and aging caused by cigarette smoke.
research LB1672 Senescent melanocytes in nevus skin stimulate hair growth
research Senescence-induced reparative fibroblasts enable scarless wound healing in aged murine skin.
Older mice heal wounds without scars due to special fibroblasts.
research Continuous MEK inhibition by AZD6244 (ARRY-142886) results in exhaustion of the cutaneous keratinocytic stem cell pool and resembles senescence driven skin aging
AZD6244 treatment causes skin aging effects by depleting skin stem cells.
research 138: Induction of cellular senescence and hair follicle stem cell dysfunction upon p14ARF and p16Ink4a expression in the skin
p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.
research The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model
Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.
research Oleanolic acid alleviates stress-induced alopecia via modulating brain-skin axis: Neuroprotection and dermal papilla cell senescence
research 76 N,N-Dimethylglycine Sodium Salt as a Multifaceted Skin Agent Targeting Skin Inflammation, Microvascular Biology, and Senescence-Driven Hair Loss
research Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts
Azithromycin and Roxithromycin can remove aging cells and may help with anti-aging.
research Aged Skin Cells Nurture Stem Cells toward Regeneration
Aged skin cells can help hair growth by stimulating stem cells.
research Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research 090 Reactive lipids from the secretome of senescent fibroblasts modify the extracellular matrix with functional consequences for resident cells
Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Author response: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
research Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles
The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes
OR2AT4 helps reduce aging and cell damage in human skin cells.
research Exploring Human Skin Aging at the Single-Cell Level
Middle-aged skin shows aging signs, and quercetin might help delay them.
research Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin
Atelocollagen boosts collagen production and improves skin elasticity in aged skin.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Senotherapeutic Potential of Araliadiol in Senescent Human Dermal Fibroblasts: An In Vitro Study Using Three Senescence Models
Araliadiol may help reduce skin aging and inflammation without killing cells.
research Editorial: Inflammation, stem cells and wound healing in skin aging
Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
research 1430 Modeling the onset of senescence associated secretory phenotype predicts therapeutic targets
The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
research Embryonic NIPP1 depletion in keratinocytes triggers a cell-cycle arrest and premature senescence in adult mice
Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.
research Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation
Stem cell vesicles can reduce skin aging from UVB by lowering inflammation and oxidative stress.
research Anti-ageing effect of a lactococcal strain: analysis using senescence-accelerated mice
Lactococcus lactis strain H61 may reduce some ageing symptoms.