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Author Response: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research Author Response: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

February 2024

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene

1 citations , January 1992 in “DNA sequence”

Researchers found a non-functional sheep keratin gene due to mutations.

research Identification de 2 polymorphismes génétiques (SNPs) associés aux spondylarthropathies (SpA) dans le locus SPA2 (9q31-34)

October 2007 in “Revue du Rhumatisme”

research Defective trophoblast function in mice with a targeted mutation of Ets2

301 citations , May 1998 in “Genes & Development”

Ets2 gene is crucial for placental development in mice.

research Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development

6 citations , June 2021 in “Developmental biology”

Dermal EZH2 controls skin cell development and hair growth in mice.

research Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation

694 citations , April 2000 in “Nature genetics”

Msx2 deficiency in mice leads to bone growth and organ development problems.

research Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis

June 2023 in “Journal of biological chemistry/The Journal of biological chemistry”

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

research 026 Altered Skin Wound Healing in Homeobox Gene Msx-2 Knockout Mice

June 2008 in “Wound Repair and Regeneration”

Msx-2 gene removal speeds up skin wound healing in mice.

Formulation Development and Investigations on Therapeutic Potential of Nanogel from Beta Vulgaris L. Extract in Testosterone-Induced Alopecia

research Formulation Development and Investigations on Therapeutic Potential of Nanogel from Beta vulgaris L. Extract in Testosterone-Induced Alopecia

2 citations , January 2023 in “BioMed Research International”

Beetroot extract nanogel may help treat hair loss caused by testosterone.

research The KRAB domain zinc finger protein, Zfp157, is expressed in multiple tissues during mouse embryogenesis and in specific cells in adult mammary gland and skin

8 citations , January 2013 in “genesis”

Zfp157 is active in many mouse tissues during development and in specific adult cells.

research MOESM1 of A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse

January 2017

research Mesenchymal cell specific deletion of Tsc2 regulates hair follicle development and patterning

September 2016 in “Journal of dermatological science”

TSC2 is crucial for proper hair follicle development and patterning.

research Genetic association of complement component 2 polymorphism with systemic lupus erythematosus

12 citations , July 2015 in “Tissue Antigens”

The A allele of the C2 gene increases the risk of lupus, while the G allele may protect against it.

research Zeb2 recruits HDAC–NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination

133 citations , June 2016 in “Nature Neuroscience”

Zeb2 is crucial for nerve repair by controlling Schwann cell function.

research Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors

14 citations , February 2018 in “Psychoneuroendocrinology”

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

research Synthesis of porcine pCLCA2 protein during late differentiation of keratinocytes of epidermis and hair follicle inner root sheath

13 citations , September 2012 in “Cell & tissue research/Cell and tissue research”

pCLCA2 protein may help maintain skin structure and function.

research Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ⁵-Δ⁴-lsomerase in Human Adrenals and Gonads

354 citations , August 1991 in “Molecular Endocrinology”

Human adrenals and gonads have a unique enzyme for steroid hormone production.

research Identification and Characterization of Two Se6OMTs from Stephania epigaea Offer Novel Insights into the Biosynthetic Pathway of Cepharanthine

3 citations , February 2025 in “Metabolites”

The research found enzymes in Stephania epigaea that help make cepharanthine.

ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

February 2024

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

research Expression and localization of Artemis serine 516 phosphorylation in human scalp skin

5 citations , August 2012 in “Experimental Dermatology”

Artemis phosphorylation at Ser516 may help regulate skin and hair structures.

research Genetic effects of vascular endothelial growth factor and its receptor 2 on feather maturity in three chicken breeds

1 citations , January 2019 in “British Poultry Science”

VEGF and VEGFR-2 genes influence feather maturity, and specific genetic markers can improve chicken breeding.

research A homozygous nonsense mutation identified in COL7A1 in a family with autosomal recessive dystrophic epidermolysis bullosa

September 2024 in “Journal of Medicine and Life”

A specific gene mutation causes a severe skin disorder in a family.

research Msx2 Prevents Stratified Squamous Epithelium Formation in the Enamel Organ

18 citations , June 2018 in “Journal of Dental Research”

Msx2 is essential for proper enamel formation by preventing abnormal cell transformation.

research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis

February 2022 in “Research Square (Research Square)”

High TSPEAR levels in colorectal cancer predict worse outcomes.

research Side gland of Suncus murinus as a new model of sebaceous gland: 5?-reductase, androgen receptor, and nuclear androgen content in male and female animals

7 citations , January 1989 in “Archives of Dermatological Research”

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

research A temperature-sensitive FERONIA mutant allele that alters root hair growth

37 citations , December 2020 in “PLANT PHYSIOLOGY”

A mutant FERONIA gene affects root hair growth at high temperatures.

research IRF2BP2 genes provide new insights into coat type and fiber composition variation in sheep

February 2026 in “Small Ruminant Research”

The IRF2BP2 gene affects sheep fleece quality by influencing fiber traits.

research 732 Ceramide synthase 4 controls epidermal lipid composition and barrier function

April 2018 in “Journal of Investigative Dermatology”

Ceramide synthase 4 is essential for maintaining skin barrier health.

research Armadillo Repeat Only Proteins Are Crucial for the Function of Plant CNGC Channels

January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)”

Armadillo Repeat Only proteins are essential for proper plant growth and response by regulating calcium channels.

research 666 Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in follicular dystrophy and primary cicatricial alopecia

April 2018 in “Journal of Investigative Dermatology”

Mutations in Far2 mice cause hair loss due to sebaceous gland issues.

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