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GlossaryShort QT Syndrome

genetic heart condition causing abnormally short QT interval

Short QT Syndrome (SQT) is a rare genetic heart condition characterized by an abnormally short QT interval on an electrocardiogram (ECG), which can lead to an increased risk of arrhythmias, fainting, and sudden cardiac death. This condition is caused by mutations in genes that affect the electrical activity of the heart, and it often requires medical management to prevent life-threatening complications.

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Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study

research Clinical characterization of men with long QT syndrome and torsades de pointes associated with hypogonadism: A review and pharmacovigilance study

17 citations , August 2019 in “Archives of Cardiovascular Diseases”

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

research Androgenic Effects on Ventricular Repolarization

64 citations , August 2019 in “Circulation”

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

research Atypical Progeroid Syndrome due to Heterozygous Missense LMNA Mutations

115 citations , October 2009 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

research Reporting on Adverse Clinical Events

October 2008 in “Clin-alert”

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

research Genomics

3 citations , June 2004 in “Critical Care Nurse”

Genomics can improve patient care by using DNA to create personalized treatment plans.

Indirect Clinical Markers for the Detection of Anabolic Steroid Abuse Beyond Conventional Doping Control in Athletes

research Indirect clinical markers for the detection of anabolic steroid abuse beyond the conventional doping control in athletes

9 citations , March 2019 in “European Journal of Sport Science”

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Post-Finasteride Syndrome: When Will We Get the Courage to Fight the Dictating Pharma Industry Despite Awareness of Sexual, Neurological, and Metabolic Side Effects in Young Men for Over a Decade

research Post-Finasteride Syndrome – When will we Get the Courage to Fight the Dictating Pharma Industry – Despite Awareness of “Sexual, Neurological and Metabolic Side Effects in Young Men for Over a Decade”

January 2020 in “Archives of urology”

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Health Care-Related Economic Burden of Polycystic Ovary Syndrome During the Reproductive Life Span

research Health Care-Related Economic Burden of the Polycystic Ovary Syndrome during the Reproductive Life Span

414 citations , August 2005 in “The Journal of Clinical Endocrinology and Metabolism”

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

research Complications of Cushing's syndrome: state of the art

374 citations , May 2016 in “The Lancet. Diabetes & endocrinology”

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

research Cardiovascular profile of pharmacological agents used for the management of polycystic ovary syndrome

4 citations , January 2019 in “Therapeutic Advances in Endocrinology and Metabolism”

Medications for PCOS don't seem to raise heart disease risk.

research Acupuncture improves anxiety and depression in patients with polycystic ovary syndrome: a systematic evaluation and meta-analysis

January 2026 in “Frontiers in Medicine”

Acupuncture reduces anxiety and depression in women with PCOS.

research Delayed diagnosis of Kearns-Sayre syndrome in a 38-year-old male patient: a case report.

2 citations , January 2008 in “International Journal of Neuroscience”

A 38-year-old man was diagnosed late with Kearns-Sayre syndrome after being wrongly treated for epilepsy.

research Role of Endolysosomes in Severe Acute Respiratory Syndrome Coronavirus-2 Infection and Coronavirus Disease 2019 Pathogenesis: Implications for Potential Treatments

55 citations , October 2020 in “Frontiers in Pharmacology”

Targeting endolysosomes may help treat COVID-19.

research Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis

8 citations , July 2024 in “Journal of Advanced Research”

CDK inhibitors may help treat ARDS and psoriasis but need more testing for safety and effectiveness.

Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?

research Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?

January 2022 in “Function”

Studying rare genetic disorders can help us understand and treat common diseases better.

Special Collection on Inward Rectifying Potassium Channels

research Special collection on inward rectifying K⁺ channels

3 citations , January 2023 in “American journal of physiology. Cell physiology”

Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.

Quality of Life of Patients One Year After COVID-19 Diagnosis: Retrospective Study

research Qualidade de vida de pacientes após um ano do diagnóstico da COVID-19: estudo retrospectivo

January 2023

Quality of life improved after COVID-19, but ongoing health support is needed.

Philological Obfuscation: Observations on Medical Categorization and Labeling

research Philological Obfuscation

May 2009 in “South African Family Practice”

The author believes that giving medical conditions official names can sometimes overwhelm or scare patients.

research Anti-anginal and beta-adrenoceptor blocking drugs

January 1983 in “Side effects of drugs annual”

Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.

research Potassium channel openers: therapeutic potential in cardiology and medicine

25 citations , December 2001 in “Expert Opinion on Pharmacotherapy”

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

35 citations , May 2020 in “Frontiers in Pharmacology”

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

research Management of the psychological comorbidities of dermatological conditions: practitioners' guidelines

23 citations , April 2017 in “Clinical, Cosmetic and Investigational Dermatology”

Dermatologists should screen for and manage psychological issues in patients with skin conditions to improve their quality of life.

Cytostatics and Immunosuppressive Drugs: Toxicities and Management

research Cytostatics and immunosuppressive drugs

January 1989 in “Side effects of drugs annual”

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

research The Rotterdam Study: 2016 objectives and design update

336 citations , August 2015 in “European Journal of Epidemiology”

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

research Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium

15 citations , November 2020 in “Development”

Stem cells in the eye have different roles and behaviors, helping maintain and repair the eye's surface.

Anabolic Androgenic Steroids Impact on Cardiovascular Risk and Events: A Literature Review

research Anabolic androgenic steroids impact on cardiovascular risk and cardiovascular events. The literature review

April 2026 in “Quality in Sport”

Anabolic-androgenic steroids increase the risk of heart problems.

Hormonal Influences on Women's Health and Athletic Performance: Insights into the Menstrual Cycle, Menopause, Contraception, and Anabolic Steroids

research Hormonal Influences on Women's Health and Athletic Performance: Insights into the Menstrual Cycle, Menopause, Contraception, and Anabolic Steroids

December 2024 in “Quality in Sport”

Hormonal balance is vital for women's health and performance, but therapies like contraceptives and steroids have both benefits and risks.

research Systemic lupus erythematosus as a rare cause of hypercalcemia: A case report

June 2022 in “Rheumatology research”

Lupus can be a rare cause of high calcium levels in the blood.

research Sex hormones and sarcopenia in older persons

34 citations , December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care”

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

research Weight loss regimens that control for carbohydrate quality or quantity: a review

5 citations , May 2008 in “Pediatric Diabetes”

Low-glycemic index diets are beneficial for weight loss and satiety, but more research is needed on long-term effects and individualized approaches are recommended.