January 2024 in “Animals” SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.
Quercetin can boost hair follicle stem cell growth in cashmere goats, potentially improving cashmere quality.
February 2025 in “International Journal of Molecular Sciences” RIPK1 inhibitors may help prevent alopecia areata by reducing immune cell activity.
489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
344 citations
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May 2018 in “EMBO journal” Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
1 citations
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December 2022 in “Animals” Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.
39 citations
,
April 2019 in “The journal of immunology/The Journal of immunology” Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
75 citations
,
September 2016 in “EMBO journal” PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
5 citations
,
January 2024 in “Science Advances” Touch dome keratinocytes in adult skin have traits of different skin cell types.
3 citations
,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
1 citations
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November 2023 in “International Journal of Molecular Sciences” SOX18 helps sheep hair cells grow by activating a specific cell growth pathway.
11 citations
,
November 2023 in “Journal of Functional Biomaterials” The ALGCS/GO30 scaffold effectively boosts mouse spermatogonial stem cell growth.
5 citations
,
November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
59 citations
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February 2019 in “BMC Genomics” Hair length in rabbits is linked to differences in lipid metabolism and cell death.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
1 citations
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May 2023 in “European Journal of Human Genetics” Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
March 2026 in “Pigment Cell & Melanoma Research” Clear documentation and shared best practices are essential for improving research consistency in pigment cells.
6 citations
,
November 2023 in “Stem Cell Reports” Stem cells in the cornea show unexpected flexibility and have important implications for medicine.
173 citations
,
August 2015 in “Developmental cell” The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
September 2025 in “Cell Reports” Skin stretching can improve vaccine delivery through hair follicles and boost immune response.
249 citations
,
November 2018 in “Cell” TNFα helps grow and maintain liver cells in 3D culture for a long time.
1 citations
,
July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
5 citations
,
January 2023 in “Nature cell biology” A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
37 citations
,
May 2021 in “Frontiers in Cell and Developmental Biology” Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.
28 citations
,
April 2024 in “Immunity” CD80 on skin stem cells helps expand Treg cells to aid wound healing.
4 citations
,
October 2021 in “Journal of Cellular and Molecular Medicine” White blood cells and their traps can slow down the process of new hair growth after a wound.
January 2025 in “Frontiers in Cell and Developmental Biology” Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
35 citations
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July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.