research Cell fate decisions: emerging roles for metabolic signals and cell morphology
Metabolic signals and cell shape influence how cells develop and change.
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540-570 / 1000+ resultsresearch Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Myotonic Dystrophy—A Progeroid Disease?
Myotonic dystrophy may be classified as a segmental progeroid disorder.
research Interleukin 6 and STAT3 regulate p63 isoform expression in keratinocytes during regeneration
The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
research Molecular cloning, characterization, and expression of sheep FGF5 gene
Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.
research Rejuvenation: an integrated approach to regenerative medicine
Rejuvenating self-repair mechanisms could improve organ recovery in regenerative medicine.
research Mitochondrial DNA 10158T>C mutation in a patient with mitochondrial encephalomyopathy with lactic acidosis, and stroke-like episodes syndrome
A patient with a rare disease had a unique genetic mutation linked to their symptoms.
research The role of glucose metabolism in wound healing: an overview
Glucose metabolism is crucial for wound healing but can delay healing in chronic wounds due to increased stress and inflammation.
research Tail Tales: What We Have Learned About Regeneration from Xenopus Laevis Tadpoles
Xenopus laevis tadpoles can regenerate complex tail structures, offering insights for regenerative medicine.
research Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells
Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.
research Tissue-Specific Multi-Omics Integration Demonstrates Molecular Signatures Connecting Obesity to Immune Vulnerability
Obesity may weaken the immune system and increase cancer risk.
research Commonly encountered symptoms and their management in patients with cirrhosis
Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.
research An ear for an ear, but only if you are a deomyinid
Only Deomyinae rodents can regenerate complex tissues.
research Gonadal Suppressive and Cross‐Sex Hormone Therapy for Gender Dysphoria in Adolescents and Adults
Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.
research Molecular Engineering of Recombinant Protein Hydrogels: Programmable Design and Biomedical Applications
Engineered protein hydrogels improve medical treatments by mimicking natural body structures.
research Biochemistry of Vitamin B: Metabolic Regulations, Deficiency Disorders and Emerging Therapeutic Strategies
Vitamin B is essential for metabolism and health, and new therapies are improving its effectiveness.
research Dermatologic manifestations of thyroid disease: a literature review
Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
research ENZYMES
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Therapeutic Efficacy and Promise of Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles in Aging and Age-Related Disorders
Human umbilical cord stem cell vesicles may help treat aging and related diseases.
research Can Plasma Rich in Growth Factors Be Safe for Parental Use? A Safety Study in the Canine Model
PRP derivatives are likely safe for therapeutic use without harmful effects.
research Influence of conditioned media from glial cell cultures on contractility of uterine in rats of different ages
Conditioned media from glial cell cultures improved uterine contractions in older rats.
research In vitro strategies for mimicking dynamic cell–ECM reciprocity in 3D culture models
The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
research Corticotropin releasing hormone and the skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma
Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.
research Insulin-like growth factor 1 and hair growth
IGF-1 can boost hair growth by promoting cell growth and preventing cell death.
research Mesenchymal stem cell therapy for liver disease: full of chances and challenges
Mesenchymal stem cell therapy shows promise for liver disease but faces challenges in standardization and approval.
research Arabidopsis VILLIN4 is involved in root hair growth through regulating actin organization in a Ca2+‐dependent manner
VILLIN4 helps root hair growth by organizing actin with calcium.
research Comparison of CD146 +/− mesenchymal stem cells in improving premature ovarian failure
CD146 + mesenchymal stem cells are more effective for treating premature ovarian failure.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.