24 citations
,
March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
23 citations
,
July 2020 in “Aging Cell” Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
22 citations
,
June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
22 citations
,
December 2013 in “Stem cells and development” Horse skin stem cells combined with platelet-rich plasma improve skin healing.
22 citations
,
January 2010 in “Humana Press eBooks” The vitamin D receptor can affect gene activity even without its usual hormone in hair and skin.
21 citations
,
August 2017 in “Journal of veterinary internal medicine” Combining amino acid and stem cell therapy may help manage hepatocutaneous syndrome in dogs.
18 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
15 citations
,
January 2023 in “Journal of Translational Autoimmunity” Melatonin may help treat skin conditions.
14 citations
,
November 2024 in “International Journal of Molecular Sciences” YAP and TAZ proteins control skin cell growth and repair.
13 citations
,
September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
12 citations
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September 2022 in “Frontiers in Genetics” Enhancing CD8+ T cell function to induce ferroptosis in tumor cells may help treat skin melanoma.
11 citations
,
September 2016 in “Archives of Dermatological Research” People with denser forearm hair have a higher risk of certain skin cancers.
10 citations
,
May 2021 in “Clinical, cosmetic and investigational dermatology” UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.
9 citations
,
May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
9 citations
,
April 2021 in “Frontiers in Immunology” Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
8 citations
,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
8 citations
,
April 2016 in “Experimental dermatology” B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
6 citations
,
July 2025 in “Advanced Materials” Biomimetic cell membrane-coated scaffolds significantly enhance tissue regeneration by mimicking natural cellular environments.
6 citations
,
February 2022 in “Journal of immunology research” Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.
6 citations
,
March 2019 in “Medical science monitor basic research/Medical science monitor. Basic research” VEGFR-2 is active in hair follicles, sebaceous glands, sweat glands, and skin on the human scalp.
4 citations
,
October 2019 in “Skin Appendage Disorders” Gefitinib can cause hair and eyebrow darkening.
4 citations
,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
3 citations
,
September 2023 in “Stem Cell Research & Therapy” Stem cells can be used to create long-lasting skin cells for treating pigment disorders.
3 citations
,
April 2022 in “Frontiers in Physiology” Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
2 citations
,
November 2025 in “International Journal of Molecular Sciences” Balancing good and harmful microbes is key to healing chronic wounds.
1 citations
,
October 2022 in “Veterinary pathology” Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.
1 citations
,
October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
1 citations
,
September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
January 2026 in “Lab on a Chip” Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
Stem cell treatments show promise for improving skin and hair, but need more research and standardization.