research Adjuvant Therapy for Revision Rhinoplasty of Contracted Nose Using Polydeoxyribonucleotide and Invasive Bipolar Radiofrequency
Using PDRN injections and RF treatments improved revision nose surgery results without major side effects.
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research Exploring murE protein inhibitors of Tropheryma whipplei through pharmacoinformatic approaches incorporating solubility-enhancing formulation insights
[6]-Gingerdiol 3-monoacetate shows promise for treating T. whipplei infections.
research G.P.2.16 Valproate, acetylcarnitine, folic acid and vitamin B12 in spinal muscular atrophy: Preliminary data of an open-label study in children
The treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may improve muscle strength in children with SMA without significant side effects.
research Finasteride: a steroid-unsparing drug?
Adequate steroid treatment needed to limit bone loss in PMR patients.
research Smart Responsive Microneedles for Controlled Drug Delivery
Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
research Spread-out Bragg peak FLASH: quantifying normal tissue toxicity in a murine model
This study investigated the tissue-sparing effects of ultra-high dose rate (FLASH) radiation compared to conventional radiation within a Spread-out Bragg Peak (SOBP) in a murine model. Using female CDF1 mice, the study assessed acute and late radiation-induced damage, with doses ranging from 19.9-49.7 Gy for conventional and 30.4-65.9 Gy for FLASH. Results showed that FLASH radiation provided significant normal tissue protection, with a mean protection ratio of 1.40 for acute skin toxicity and 1.18 for fibrotic development. The findings confirm that FLASH radiation within the SOBP maintains its tissue-sparing benefits, offering a 40% reduction in acute skin damage and an 18% reduction in fibrotic development compared to conventional radiation.
research Evaluating the quality of studies reporting on clinical applications of stromal vascular fraction: A systematic review and proposed reporting guidelines (CLINIC-STRA-SVF)
SVF is safe and effective, but research quality is low; new guidelines are proposed to improve future studies.
research PRP for skin rejuvenation
PRP is a safe natural treatment that improves skin by reducing wrinkles and enhancing texture for up to 4 months.
research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Efficacy and Safety of Skin Radiance Collagen on Skin and Hair Matrix: A Placebo-Controlled Clinical Trial in Healthy Human Subjects
Skin Radiance Collagen improved skin and hair health in adult females.
research Repurposed Drugs
Repurposing existing drugs can save time and money in finding new treatments.
research Proximate Composition, Mineral analysis and Phytochemical Characterization of an Ethnomedicinal Plant Sphenodesme involucrata var. paniculata (C.B. Clarke) Munir
Sphenodesme involucrata var. paniculata is a safe and healthy medicinal plant with beneficial nutrients.
research Parry-Romberg Syndrome: A Rare Case with Diagnostic Challenges and Orthodontic Implications
Early recognition and multidisciplinary management are crucial for improving outcomes in Parry-Romberg syndrome.
research Human papillomavirus vaccine recombinant quadrivalent
Two women lost hair after mesotherapy for hair loss, with one having permanent and the other temporary hair loss.
research Engineered Skin Substitute Regenerates the Skin with Hair Follicle Formation
The engineered skin substitute helped grow skin with hair on mice.
research Small molecules facilitate single factor-mediated sweat gland cell reprogramming
Small molecules can help turn skin cells into sweat gland-like cells for potential skin repair.
research Re: A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Post-Finasteride Syndrome
research The Effects of Photobiomodulation on MC3T3-E1 Cells via 630 nm and 810 nm Light-Emitting Diode
LED light therapy boosts bone cell growth and function.
research Arsenic Trioxide as Effective Therapy for Relapsed Acute Promyelocytic Leukemia
Arsenic trioxide effectively treats relapsed acute promyelocytic leukemia with manageable side effects.
research Periorbital Rejuvenation: A Review of Dermatologic Treatments
Different skin treatments work best for different levels of wrinkles and sun damage.
research Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement
PRP shows promise but lacks consistent evidence and regulation.
research Dermatopathia Pigmentosa Reticularis: Report of a New Cases and Literature Review
DPR can show different hair characteristics, as seen in two brothers with normal hair.
research Looking Beyond PRP, Exosomes, and Stem Cells
Stem cells, PRP, and exosomes show promise in treating skin conditions but face regulatory and safety challenges.
research An Update on The Paradigm Shift of Regenerative Medicine
Regenerative medicine uses combined treatments to boost natural healing and improve health, especially for aging.
research Exosome Revolution or Marketing Mirage? AI-Based Multi-domain Evaluation of Claims, Scientific Evidence, Transparency, Public Sentiment, and Media Narratives
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrosis and cancer.
research Resident CD34-positive cells contribute to peri-endothelial cells and vascular morphogenesis in salivary gland after irradiation
CD34-positive cells help repair and form new blood vessels in salivary glands after radiation.
research Optimization of X-ray microplanar beam radiation therapy for deep-seated tumors by a simulation study
Using 100–300 keV X-ray energy is best for treating deep-seated tumors with microplanar beam radiation therapy.
research MP89-08 POST-FINASTERIDE SYNDROME: REAL OR IMAGINED?
Finasteride 1mg linked to diverse symptoms; other treatments improve erectile function in rats.
research Treatment of Del(5q) Myelodysplastic Syndrome with All-Trans-Retinoic Acid and Tocopherol-α.
The treatment was not recommended due to limited effectiveness and significant side effects.