October 2020 in “Journal of Pakistan Association of Dermatology” Finasteride appears safe for long-term sperm concentration, but more research is needed for clear conclusions.
49 citations
,
December 2007 in “Fertility and Sterility” Stopping finasteride improved sperm counts in two men, reducing the need for fertility treatments.
38 citations
,
December 2010 in “Fertility and Sterility” Finasteride may cause male infertility, stopping it can help.
34 citations
,
January 2004 in “Revista do Hospital das Clínicas” Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
33 citations
,
April 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
16 citations
,
January 2017 in “Asian journal of andrology/Asian Journal of Andrology” Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.
5 citations
,
December 2012 in “PubMed” Stopping the use of the drug finasteride can improve sperm count and does not prevent normal conception, but caution is advised when trying to conceive.
2 citations
,
January 2011 in “Yearbook of Urology” Stopping finasteride can improve sperm count in infertile men.
2 citations
,
September 2007 in “Fertility and Sterility” Stopping Propecia may improve sperm count and fertility.
June 2026 in “The Journal of Sexual Medicine” Finasteride 1 mg reduces semen quality without affecting hormones.
June 2026 in “British Journal of Dermatology” Finasteride mildly affects semen but is reversible; dutasteride has stronger effects with incomplete recovery.
April 2026 in “The Journal of Urology” Finasteride 1 mg/day reduces semen quality without affecting hormones or sexual function.
May 2025 in “Gynecological Endocrinology” Men with a family history of PCOS have lower sperm concentration and more hair loss.
Finasteride improves hair but may reduce sperm quality at higher doses.
May 2022 in “Research Square (Research Square)” Melatonin improved sheep reproduction, being more beneficial and cost-effective in males.
June 2018 in “The Journal of Sexual Medicine” Finasteride does not negatively affect male reproductive function.
January 2018 in “日本薬理学会年会要旨集 =” Stopping finasteride improves sperm quality but not semen volume in young men.
68 citations
,
February 2019 in “Urology” Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.
April 2021 in “Animal Bioscience” 5-Aminolevulinic acid can help chicken sperm move better at the right amount.
2 citations
,
March 2021 in “Reproduction” Finasteride may affect male fertility by interfering with specific sperm signaling.
72 citations
,
September 1975 in “Biology of Reproduction” Most zinc in rat sperm is in the tail, linked to structures similar to hair keratin.
7 citations
,
January 2009 in “DOAJ (DOAJ: Directory of Open Access Journals)” D-004 did not harm sperm cells in mice.
2 citations
,
September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
January 2024 in “Wiadomości Lekarskie” Male sperm disorders significantly contribute to infertility.
195 citations
,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
10 citations
,
September 2015 in “Folia Histochemica Et Cytobiologica” Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.
Finasteride and dutasteride can harm male reproductive health, affecting sperm and causing sexual dysfunction.
4 citations
,
September 1977 in “Lipids” Gerbils on a fat-deficient diet had altered fatty acid levels, hair loss, reduced sperm, and lower body weight.
April 2026 in “The Journal of Urology” Finasteride and dutasteride reduce semen quality, with dutasteride having a stronger negative effect.
4 citations
,
October 2000 in “Contraception” The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.