research 1322 A non-cell autonomous dermal hedgehog signaling mechanism for follicular neoplasia and induction
Mutations in the SHH pathway in certain skin cells can cause skin tumors and abnormal hair growth.
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research Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression
Chilled ATPv-supplemented saline best preserves hair grafts' key genes.
research Spatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse (Acomys) ear
The spiny mouse regenerates ear tissue asymmetrically, with gene expression differences possibly explaining its unique healing abilities.
research Estrogens
research Leydig cell hyperplasia as a cause of virilization in a postmenopausal woman: A case report
Leydig cell hyperplasia can cause virilization in postmenopausal women and is treatable with surgery.
research Androgen levels and apoptosis in the testis during postnatal development of finasteride-treated male rat offspring
Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.
research Abstracts from the 55th European Society of Human Genetics (ESHG) Conference: e-Posters
Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
research Induction of cardiomyocyte‑like cells from hair follicle cells in mice
Mouse hair follicle cells can become heart-like cells without genetic changes.
research 110 Transglutaminase 2 is a potential regulator of sebocyte maturation
Transglutaminase 2 may control sebocyte maturation and lipid metabolism.
research Androgens and the hair follicle. Cultured human dermal papilla cells as a model system.
research Hair Follicle Stem Cells
Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
research Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family
Abraham's family infertility may have a genetic explanation.
research Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata
Gonadal hormones significantly affect the severity of alopecia areata in mice.
research Study on Organ Culture of Mouse Vibrissa Follicle in Vitro
Mouse hair follicles grow best in a special medium, especially when cut and from adult mice.
research Stereographic analysis of syringomas
Syringomas likely start in the upper dermis and form distinct luminal structures.
research Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats
Agomelatine may help reduce benign prostatic hyperplasia by blocking certain inflammatory pathways.
research Intraovarian platelet-rich plasma administration could improve blastocyst euploidy rates in women undergoing in vitro fertilization
Platelet-rich plasma may improve embryo genetics in IVF.
research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
Skin-derived precursors in hair follicles come from different origins but function similarly.
research さまざまな臓器からの培養線維芽細胞による毛包誘導
Cells from skin and lung can help regenerate hair follicles.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis
ABCG2 protein marks stem-like skin cells in human epidermis.
research Harnessing the intradermal delivery of hair follicle dermal papilla cell spheroids for hair follicle regeneration in nude mice
Delivering specific cell clusters into the skin can help regrow hair in mice.
research Hyperprogesteronemia associated with Sertoli cell tumor and alopecia in a dog
Castration helped a dog with a tumor and hair loss by normalizing hormone levels and regrowing hair.
research 574 Murine sebaceous gland homeostasis requires intact cutaneous innervation in a hair cycle-dependent context
Mouse skin glands need healthy nerves to grow properly during hair growth phases.
research Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research Ganoderma lucidum is an inhibitor of testosterone-induced prostatic hyperplasia in rats
Ganoderma lucidum may help treat enlarged prostate in rats.
research Stem cells supporting other stem cells
Stem cells can help other stem cells by producing supportive factors.
research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells
Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
research Prostaglandins in androgenetic alopecia in 12 men and four female
research Functional salivary gland regeneration by transplantation of a bioengineered organ germ
Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.