research MP09-17 METHYLATION OF SRD5A2 IN THE BLOOD AS A NOVEL BIOMARKER TO PREDICT SENSITIVITY TO 5-ARI TREATMENT
SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.
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360-390 / 1000+ results research Peimine Promotes Skin Wound Repair in Mice by Activating the Notch1 Signaling Pathway in Fibroblasts
Peimine helps heal skin wounds by activating a specific cell signaling pathway.
research Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
Blocking progesterone metabolism can cause depression-like behavior in mice.
research Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride
Progesterone boosts alcohol's effect on brain, finasteride counters it.
research TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network
TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.
research Trapa bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice
Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.
research Nucleus‐specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research Effect of a novel steroid (PM-9) on the inhibition of 5α-reductase present in Penicillium crustosum broths
PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
research The effect of finasteride on spermatogenesis of Mesocricetus auratus
Finasteride causes sperm production decrease in Mesocricetus auratus.
research Expression of MsPG3‐GFP fusions in Medicago truncatula‘hairy roots’ reveals preferential tip localization of the protein in root hairs
MsPG3 protein gathers at root hair tips, aiding growth.
research Isolation and Structural Characterization of Finasteride Degradation Products by Preparative HPLC, HRMS, and NMR
Finasteride breaks down into new compounds under acidic conditions.
research Neuroactive steroids induce changes in fetal sheep behavior during normoxic and asphyxic states
Neurosteroids help protect fetal brains from asphyxia damage.
research Possible involvement of 5α-reduced neurosteroids in adrenergic and serotonergic stimulation of GFAP gene expression in rat C6 glioma cells
5α-reduced neurosteroids may help regulate glial cell differentiation.
research ISID1116 – Novel androgen receptor degrader for androgenetic alopecia (AGA) application
research The Safety and Efficacy of a Novel Saw Palmetto ( Serenoa repens ) Extract for Promoting Hair Growth in Adults With Self‐Perceived Thinning Hair: 180‐Day Results
SEREVELLE safely and effectively promotes hair growth in adults with thinning hair.
research N,N-Dimethylglycine sodium salt prevents human dermal papilla senescence and promotes hair growth in patients with pattern hair loss
The study examines the effects of N,N-Dimethylglycine sodium salt (DMG-Na) on hair growth and dermal papilla cell senescence. In vitro, DMG-Na was found to prevent senescence in dermal papilla cells by inhibiting senescence markers. In two clinical trials with over 300 participants, topical DMG-Na significantly improved hair density and reduced hair shedding over 6 months. The treatment was effective in both men and women, suggesting DMG-Na as a promising agent for managing hair loss by enhancing cell growth and mitigating oxidative stress.
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research Finasteride 1 mg in alopecia: sexual dysfunction, suicidal ideation. Providing balanced information to male patients is key.
research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells
research Determination of Free Chemical Potential for Finasteride Diffusion through SDS Micelle Suggested as Alternative Living Membrane System
Finasteride diffuses spontaneously through SDS micelles, suggesting they can replace living cell membranes.
research Inhibition of 5α‐Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice
Finasteride reduces alcohol consumption in mice by affecting brain chemicals.
research Secondary infertility due to use of low-dose finasteride
Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.
research Buyiniuxi pill promotes hair regrowth in a DHT-induced mouse model of androgenetic alopecia
research (798) Finasteride 1 mg: Silent Impacts on Male Fertility Despite Preserved Hormonal Balance
Finasteride 1 mg reduces semen quality without affecting hormones.
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research Physiological and histological study of the effect of finasteride drug (Prostacare) on the fertility of albino male rats
Finasteride significantly reduces fertility in male rats.
research In Vitro Antibacterial and Antioxidant Activities, Pharmacokinetics, and In Silico Molecular Docking Study of Phytochemicals from the Roots of Ziziphus spina-christi
Compounds from Ziziphus spina-christi roots show strong antibacterial and antioxidant potential.