July 2026 in “Acta Biomaterialia” A method was developed to create early-stage hair structures in lab-grown skin.
40 citations
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June 2019 in “Biochemical and Biophysical Research Communications” CHIR99021 helps create human skin with hair follicles, offering hope for hair loss treatments.
July 2022 in “Institutional Repositories DataBase (IRDB)” 3D spheroid cells effectively test hair growth compounds like Minoxidil.
November 2021 in “Research Square (Research Square)” 3D spheroid cultures of human hair follicle cells are better for hair growth research than 2D cultures, and they provide new insights into how hair growth treatments like minoxidil and TCQA work.
June 2023 in “Lithuanian University of Health Sciences”
April 2018 in “Journal of Investigative Dermatology” Culturing Dermal Papilla Cells and Hair Follicle Stem Cells in 3D conditions can significantly improve hair regeneration potential.
65 citations
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January 2021 in “Burns & Trauma” Bioprinting and spheroid culture can create a skin model with regenerating sweat glands and hair follicles.
9 citations
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March 2018 in “Journal of the Formosan Medical Association” Chitosan enhances melanocyte growth and function better than PVA.
The method effectively creates uniform, viable cell spheroids for 3D cell culture.
July 2025 in “Burns & Trauma” 3D cell spheroids can help reduce scars by delivering therapeutic vesicles.
Melatonin may help hair growth by affecting certain cell signals, and the paper improved after revisions.
June 2019 in “Problems of Cryobiology and Cryomedicine” Encapsulating hair follicle cells in a special gel boosts their activity.
July 2024 in “Journal of Investigative Dermatology”
December 2024 in “Biomaterials Research” Delivering specific cell clusters into the skin can help regrow hair in mice.
January 2019 in “CLINICAL AND EXPERIMENTAL MORPHOLOGY”
April 2016 in “Journal of Investigative Dermatology” Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.
36 citations
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January 1994 in “Cell and Tissue Research” November 2025 in “Journal of Investigative Dermatology” Minoxidil helps hair growth by improving blood vessel function.
April 2026 in “Biomedical and Biotechnology Research Journal (BBRJ)” 3D culture better preserves key properties of hair follicle cells for regeneration.
November 2025 in “Stem Cell Reviews and Reports” The error in figures didn't affect the study's results or conclusions.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” A new Wnt surrogate specifically targets the Frizzled7 receptor, promoting organoid formation and hair growth.
January 2024 in “UVic’s Research and Learning Repository (University of Victoria)” A permanent hair system on the scalp is suggested to address challenges in 3D bioprinting hair follicles.
January 2020 in “Open University of Cape Town (University of Cape Town)” Efficient culture methods are needed to keep human keratinocytes undifferentiated for hair follicle induction.
January 2024 in “Biomaterials Research” The new 3D system helps test hair growth treatments effectively.
September 2019 in “Journal of Investigative Dermatology” Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
1 citations
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February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A peptide from hair follicle stem cells promotes hair growth by activating specific skin cells.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
August 2016 in “Journal of Investigative Dermatology” DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
April 2016 in “Journal of Investigative Dermatology” Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.