research NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor
NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
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research Androgen Secreting Steroid Cell Tumor of the Ovary Represented with Postmenopasal Bleeding and Extensive Hirsutism
A woman's excessive hair growth and high testosterone were caused by a rare ovarian tumor, which was successfully treated with surgery.
research The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model
Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.
research Imbalanced redox dynamics induce fibroblast senescence leading to impaired stem cell pools and skin aging
Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
research Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease
Basal cell carcinomas need extra mutations to grow from small to large tumors.
research Application of Advanced Platelet-Rich Fibrin in Oral and Maxillo-Facial Surgery: A Systematic Review
Advanced platelet-rich fibrin improves healing and reduces pain in oral surgery.
research Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats
HGF-modified hair follicle stem cells help brain recovery after injury in rats.
research Characterization and functional analysis of Krtap11-1 during hair follicle development in Angora rabbits (Oryctolagus cuniculus)
research Targeted cell delivery of mesenchymal stem cell therapy for cardiovascular disease applications: a review of preclinical advancements
New methods improve stem cell delivery for heart disease, but challenges remain.
research Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review
Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
research A Receptor-Like Kinase Mediates Ammonium Homeostasis and Is Important for the Polar Growth of Root Hairs inArabidopsis
The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.
research Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network
LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.
research Light Sheet Fluorescence Microscopy Quantifies Calcium Oscillations in Root Hairs ofArabidopsis thaliana
Light sheet fluorescence microscopy effectively measures calcium changes in Arabidopsis root hairs.
research The evaluation of endothelial function with flow-mediated dilatation and carotid intima media thickness in young nonobese polycystic ovary syndrom patients; existence of insulin resistance alone may not represent an adequate condition for deterioration of endothelial function
Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.
research Essential Oil and Important Activities ofThuja orientalisandThuja occidentalis
Thuja orientalis and Thuja occidentalis essential oils have medicinal properties useful for developing treatments with antimicrobial and bioactive effects.
research Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers
Innovative biomaterials show promise in healing chronic diabetic foot ulcers.
research Editorial: Hair Follicle Stem Cell Regeneration in Aging
Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
research Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata
SCD-153 shows promise as an effective topical treatment for alopecia areata.
research Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype
Aging reduces dermal sheath cells, affecting youthful skin appearance.
research The potential of regulatory T cell-based therapies for alopecia areata
Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Modulation of T Cell Responses by Fucoidan to Inhibit Osteogenesis
Fucoidan reduces bone cell formation by affecting T-cell activity.
research The acyl-CoA binding protein is required for normal epidermal barrier function in mice
ACBP is crucial for healthy skin in mice.
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma
Lower SMAD2/3 activation predicts more severe skin cancer.
research Developmental and functional roles of androgen and interactive signals for external genitalia and erectile tissues
Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research Enhancing hair regrowth using rapamycin-primed mesenchymal stem cell-derived exosomes
Rapamycin-primed exosomes can significantly boost hair regrowth.
research Hair follicle stem cell-derived secretome protects astrocytes in an in vitro ischemia/reperfusion model
Hair follicle stem cell secretions may help protect brain cells and improve stroke recovery.
research Role of Extracellular Vesicles as Mediators of Cell Communication and Novel Biomarkers in Sepsis
Small extracellular vesicles can help diagnose and manage sepsis.