research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
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research Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
research Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances
Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
research Advances in skin grafting and treatment of cutaneous wounds
Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
research Cutaneous extramedullary haematopoiesis: Implications in human disease and treatment
Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.
research Melanocytes in regenerative medicine applications and disease modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Extracellular vesicles in age-related diseases: disease pathogenesis, intervention, and biomarker
Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
research Regenerative medicine in aesthetics
Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.
research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
research Epithelial stem cells and implications for wound repair
Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
research Exosomes in Cosmetic Dermatology: A Review of Benefits and Challenges
Exosomes could improve skin and hair treatments, but more research and regulation are needed.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Regulatory, Ethical, and Safety Considerations of Exosome‐Based Therapies in Dermatology
Exosome-based therapies in dermatology show promise but face challenges in standardization, regulation, and safety.
research Autologous Regenerative Therapy in Baldness Surgery
Autologous Regenerative Therapy may improve hair restoration by using stem cells from fat.
research Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights
Changes in scalp microbes may contribute to hair loss, suggesting new treatment options.
research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
research Mommy — where do tumors come from?
Some skin tumors may start from hair follicle stem cells.
research JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia
Targeting JAK-STAT1 can reduce inflammation and promote hair growth in conditions linked to EGFR deficiency.
research The expanding impact of T-regs in the skin
T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
research Human Hair Graying Revisited: Principles, Misconceptions, and Key Research Frontiers
Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
research Distinct tooth regeneration systems deploy a conserved battery of genes
Different species use the same genes for tooth regeneration.
research Exosome-Based Therapies for Alopecia Areata: A Systematic Review of Clinical and Experimental Evidence
Exosome-based therapies show promise for treating alopecia areata but need more research.
research Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
research Management of androgenetic alopecia: a review
Combination therapies are more effective for treating androgenetic alopecia than single treatments.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research Low fucosylation defines the glycocalyx of progenitor cells and melanocytes in the human limbal stem cell niche
Low fucosylation boosts stem cell growth in the eye.
research Drug-Loaded Extracellular Vesicle-Based Drug Delivery: Advances, Loading Strategies, Therapeutic Applications, and Clinical Challenges
EV-based drug delivery shows promise but faces challenges in standardization and scalability.
research Differentiation of Adipose Derived Stem Cells by Stimulating with Extracellular Vesicles Secreted from Dermal Papilla Cells Activated with Osteogenic and Adipogenic Inducers
Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.
research Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells
Injected human hair follicle cells can create new, small hair follicles in skin cultures.
research Exploring the dermatological applications of human mesenchymal stem cell secretome: a comprehensive review
MSC-derived conditioned media can improve skin treatments.