10 citations
,
October 2019 in “Iranian Biomedical Journal” Simvastatin helps hair follicle stem cells turn into skin cells.
August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
May 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” PPARgamma is crucial for healthy hair follicles, and its loss causes scarring alopecia.
11 citations
,
December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
7 citations
,
July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
6 citations
,
September 2017 in “Experimental and Therapeutic Medicine” Shortened PEDF peptides speed up skin wound healing by boosting cell growth.
1 citations
,
July 2023 in “Chinese Medicine” Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
1 citations
,
April 2023 in “Animals” Wnt and BMP pathways stimulate hair growth in Min pigs, with Wnt being more effective.
1 citations
,
February 2023 in “Journal of Cellular Biochemistry” Cardiomyocyte-derived media can inhibit lung cancer cell growth and movement.
SMAD4 is crucial for muscle repair in young adults but not in aged mice.
April 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.
74 citations
,
October 2023 in “Nature Reviews Molecular Cell Biology” 10 citations
,
January 2023 in “Journal of Orthopaedic Surgery and Research” Panax notoginseng saponins with stem cells improve healing and reduce inflammation in diabetic ulcers.
2 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.
November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.
2 citations
,
December 2022 in “Bio-Design and Manufacturing” A new portable microscope can effectively monitor skin wound healing in real-time.
January 2024 in “Journal of Tissue Engineering” A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
13 citations
,
September 2014 in “BMC Complementary and Alternative Medicine” Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.
1 citations
,
April 2024 in “Cells” Corneal cells can potentially revert to stem cells, aiding in repair and regeneration.
56 citations
,
July 2014 in “PloS one” SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
1 citations
,
April 2023 in “World Journal of Urology” Finasteride reduces some inflammation in BPH but not all.
8 citations
,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
22 citations
,
July 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
April 2019 in “Journal of Investigative Dermatology” Eating grape powder may reduce the severity of skin allergy symptoms.
67 citations
,
December 2009 in “Stem Cells” β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.
35 citations
,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
59 citations
,
October 2020 in “Stem Cell Reviews and Reports” Men have higher COVID-19 mortality rates than women due to biological and lifestyle factors.