August 2023 in “International journal of medical science and clinical research studies” PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.
November 2025 in “Journal of Investigative Dermatology” Alopecia Areata may involve reduced antioxidant defenses in hair follicles, affecting stem cell function.
53 citations
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February 2015 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is essential for normal hair growth and preventing hair loss.
33 citations
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April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
19 citations
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September 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become smooth muscle cells using specific growth factors.
9 citations
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November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
6 citations
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April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
4 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” DLX5 helps hair follicle stem cells differentiate by activating a specific pathway.
1 citations
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May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
1 citations
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October 2022 in “Molecular therapy” The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.
June 2026 in “Journal of Sulaimani Medical College” Adipose-derived stem cell exosomes are more effective and satisfying for treating hair loss than minoxidil.
February 2026 in “BMC Plastic and Reconstructive Surgery” Induced pluripotent stem cells could improve chronic wound healing but face safety and effectiveness challenges.
June 2025 in “Cell Metabolism” Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
May 2025 in “International Journal of Molecular Sciences” Exosomes from rat hair follicle stem cells may help heal wounds and regenerate skin.
December 2024 in “International Journal of Molecular Sciences” Human umbilical cord stem cell vesicles may help treat aging and related diseases.
July 2024 in “Journal Of Stem Cell Research” Mesenchymal stem cells improve skin appearance and structure in dermatology and aesthetic medicine.
December 2023 in “Medical Times” The MEST method increases cell yield and volume for regenerative medicine but needs more testing.
August 2025 in “BMC Research Notes” iPSC lines from different tissues share a common miRNA profile, supporting their pluripotent nature.
February 2023 in “International Journal of Molecular Sciences” Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
21 citations
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November 2015 in “Phytomedicine” Glycyrrhizic acid may help reduce unwanted hair growth.
200 citations
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March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
60 citations
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June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
20 citations
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November 2021 in “Biomedicines” Adipose-derived stem cells show promise in treatments but need more research for safety, especially in cancer.
10 citations
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June 2021 in “EMBO reports” When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.
3 citations
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December 2022 in “npj Regenerative Medicine” HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
1 citations
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November 2024 in “Bone Reports” Cellularity can estimate mesenchymal stem cell concentration in bone marrow, aiding regenerative medicine.
1 citations
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April 2022 in “Frontiers in Bioengineering and Biotechnology” Astrocytes can become stem cell-like and help repair brain damage.
February 2026 in “Chemical Engineering Journal” PCA hydrogel promotes hair growth by enhancing blood vessel formation and hair follicle stem cell activity.
September 2025 in “Journal of Investigative Dermatology” SLC3A2 is crucial for hair follicle stem cell function and hair growth.
April 2025 in “Journal of Investigative Dermatology” Two microRNAs in stem cell exosomes help treat hair loss by targeting a specific signaling pathway.