9 citations
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July 2021 in “Essays in Biochemistry” Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
6 citations
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July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
317 citations
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April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
65 citations
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April 2018 in “Oncotarget” Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
53 citations
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July 2014 in “American Journal of Physiology-Endocrinology and Metabolism” Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.
30 citations
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June 2010 in “Endocrine Related Cancer” SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.
11 citations
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May 2024 in “Reproductive Biology and Endocrinology” Fetal ovaries produce different hormones than adult ovaries, and endocrine-disrupting chemicals may affect this process.
5 citations
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April 2024 in “ACS Chemical Neuroscience” A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.
4 citations
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January 2023 in “Marine Drugs” Marine compounds from gorgonians and soft corals show promise for drug development, especially for chronic disorders.
4 citations
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December 2021 in “Pharmacological Reports” Metformin is less effective in men with early-onset hair loss.
A balanced diet is crucial for normalizing hormone levels and managing obesity-related issues.
July 2025 in “Food Science & Nutrition” Vitamin D supplements improve hair growth and metabolism in rabbits.
August 2023 in “Medicina-lithuania” Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.
January 2017 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” Short-term diabetes can cause changes in brain steroids, cholesterol balance, and mitochondrial function.
11 citations
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November 2021 in “International journal of molecular sciences” Gut microbes significantly affect brain steroid levels.
3 citations
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October 2021 in “Clinica Chimica Acta” Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.
13 citations
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April 1994 in “Baillière's clinical endocrinology and metabolism” Some people have genetic mutations that make them resistant to vitamin D, leading to rickets even with enough vitamin D intake.
January 2022 in “Surgical and Cosmetic Dermatology” People with androgenic alopecia (AGA) have a higher chance of getting metabolic syndrome.
December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
97 citations
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April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
13 citations
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November 2014 in “Toxicology Letters” Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
2 citations
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August 2025 in “Harm Reduction Journal” Non-medical steroid use in gym-goers is risky and needs better prevention and care strategies.
December 2025 in “Experimental Dermatology” Improving blood vessel health and controlling uric acid may help manage alopecia areata.
August 2023 in “Fermentation” Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.
49 citations
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September 2015 in “Psychoneuroendocrinology” 5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.
32 citations
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September 2010 in “Stress” Neurosteroids help protect fetal brains from asphyxia damage.
26 citations
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August 2021 in “Medicine” Low testosterone and SHBG levels are linked to higher COVID-19 death rates.
10 citations
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May 2025 in “Nutrition & Metabolism” Metabolic syndrome is linked to skin diseases, requiring integrated treatment and monitoring.
1 citations
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February 2023 in “Plants” BB4CMU rice bran oil may help treat hair loss and gray hair.
1 citations
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August 2021 in “Frontiers in Genetics” Certain genes related to sulfur metabolism are more active during the growth phase of Cashmere goat wool, and melatonin might help this process.