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Higher ACE2 levels in certain tissues may worsen COVID-19 in people with other health issues, especially older adults.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.

Anabolic-androgenic steroids can harm women's health and their offspring.

Anabolic-androgenic steroids can damage the brain, causing mood and cognitive problems.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

Reduced plakoglobin and steroid abuse increase the risk of heart rhythm issues.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Antiandrogens block male hormones and are not safe during pregnancy.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Adrenarche increases adrenal androgens around age 6, affecting hair growth and development.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.

Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

MMP-19 may worsen skin diseases by affecting skin growth and inflammation.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Natural antioxidants like flavonoids and resveratrol may help prevent low testosterone in aging men.

Methotrexate alone is as effective and safe as combining it with prednisolone for treating Lichen planopilaris.

A man developed autoimmune issues after a transplant, improved with treatment, but died from leukemia relapse.

Xiaozhi Yufa decoction may help treat hair loss by improving hair growth and reducing inflammation.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.