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GlossaryStomatitis

inflammation of mouth's mucous membranes causing sores and discomfort

Stomatitis is the inflammation of the mucous membranes in the mouth, which can cause symptoms like redness, swelling, and sores. It can result from various factors, including infections, irritants, or underlying health conditions, and may affect eating, speaking, and overall oral health.

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research Potential of Natural Products in Hangeshashinto Water Extract on the Direct Suppression of Stomatitis Induced by Intra-/Extracellular Advanced Glycation End-Products

September 2025 in “International Journal of Molecular Sciences”

Hangeshashinto's natural products may help treat stomatitis by reducing inflammation and cytotoxicity.

Fatigue, Alopecia, and Stomatitis Among Patients With Breast Cancer Receiving Cyclin-Dependent Kinase 4 and 6 Inhibitors: A Systematic Review and Meta-Analysis

research Fatigue, alopecia and stomatitis among patients with breast cancer receiving cyclin-dependent kinase 4 and 6 inhibitors: a systematic review and meta-analysis

28 citations , July 2017 in “Expert Review of Anticancer Therapy”

Breast cancer patients taking CDK4/6 inhibitors are more likely to experience fatigue, hair loss, and mouth sores.

research Fever, Maculopapular Rash and Severe Aphthous Stomatitis in a Renal Transplant Patient

December 2013 in “American journal of transplantation”

The patient improved after antiviral treatment for a viral infection.

Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

research Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

1461 citations , March 2004 in “Annals of oncology”

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

research First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors

505 citations , October 2011 in “Journal of clinical oncology”

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails

179 citations , October 2018 in “American Journal of Clinical Dermatology”

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

research Cutaneous complications of chemotherapeutic agents

172 citations , November 1983 in “Journal of The American Academy of Dermatology”

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer

108 citations , December 2003 in “Clinical breast cancer”

PLD is an effective and safer alternative for treating breast cancer.

$Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer$

research Doxil (Caelyx): an exploratory study with pharmacokinetics in patients with hormone-refractory prostate cancer

81 citations , February 2000 in “Anti-cancer drugs”

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

research Mucocutaneous side effects of antineoplastic chemotherapy

55 citations , November 2004 in “Expert opinion on drug safety”

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

research Taiwanese Dermatological Association consensus for the prevention and management of epidermal growth factor receptor tyrosine kinase inhibitor-related skin toxicities

22 citations , March 2017 in “Journal of the Formosan Medical Association”

The guidelines help doctors manage skin problems from certain cancer treatments to improve patients' lives.

research Colchicine in Managing Skin Conditions: A Systematic Review

21 citations , January 2022 in “Pharmaceutics”

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

research [Cutaneous manifestations of zinc deficiency in ethylic cirrhosis].

18 citations , January 1987 in “PubMed”

Zinc deficiency in alcoholic cirrhosis patients causes skin issues and other symptoms, which improve with zinc treatment.

Cutaneous Adverse Reactions Linked to Targeted Anticancer Therapies Bortezomib and Lenalidomide for Multiple Myeloma: New Drugs, Old Side Effects

research Cutaneous adverse reactions linked to targeted anticancer therapies bortezomib and lenalidomide for multiple myeloma: new drugs, old side effects

18 citations , May 2013 in “Cutaneous and Ocular Toxicology”

The cancer drugs bortezomib and lenalidomide cause skin side effects in many patients.

research Pay-For-Delay Settlements in theWake of Actavis

January 2014 in “Michigan telecommunications and technology law review”

Zinc deficiency in alcoholic cirrhosis patients causes skin issues, and zinc treatment improves symptoms.

Cutaneous and Mucosal Side Effects of New Anticancer Drugs: EGF-R Inhibitors, Tyrosine Kinase Inhibitors, and Mitotic Spindle Stabilizers

research Effets secondaires cutanéo-muqueux des nouvelles molécules anticancéreuses: Inhibiteurs de l'EGF-R, inhibiteurs de tyrosine kinase et stabilisateurs du fuseau mitotique

January 2011

New cancer drugs can cause skin side effects like rashes, dry skin, hair changes, and nail problems.

research Cutaneous Toxicities From Transplantation-Related Medications

14 citations , April 2017 in “American Journal of Transplantation”

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

research Melasma and other skin manifestations or oral contraceptives.

10 citations , January 1967 in “PubMed”

Oral contraceptives often cause melasma and other skin issues.

research Investigation of Oral Mucosal Lesions in Patients Attending Dermatology Outpatient Clinic: A Study of 1670 Cases

January 2016 in “Türkiye klinikleri tıp bilimleri dergisi”

About 38% of patients at a dermatology clinic had oral lesions, with coated tongue, fissured tongue, and Fordyce granules being most common.

research Clinical recognition and therapeutic treatment options for cutaneous epitheliotropic lymphoma in dogs

October 2010 in “eCommons (Cornell University)”

Cutaneous epitheliotropic lymphoma in dogs is often misdiagnosed but can be treated with chemotherapy and alternative therapies.

research Biotinidase Deficiency and Seizures

June 1987 in “Pediatric Neurology Briefs”

Biotinidase deficiency can cause symptoms like sleepiness, hair loss, and seizures.

research Comparison of patients’ diagnoses in a dermatology outpatient clinic during the COVID‐19 pandemic period and pre‐pandemic period

16 citations , December 2020 in “International Journal of Clinical Practice”

The pandemic changed how often certain skin conditions were diagnosed.

research Management of adverse events and other practical considerations in patients receiving capecitabine (Xeloda®)

35 citations , January 2004 in “European journal of oncology nursing”

Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.

research Predictive factors for therapeutic response and cluster analysis in syndrome of undifferentiated recurrent fever (SURF)

2 citations , July 2025 in “RMD Open”

IL-1 blockade is effective for treating SURF, and personalized treatment is needed.

research Reversible hypopigmentation of hair secondary to Vitamin B12 deficiency

1 citations , January 2013 in “Nasza Dermatologia Online”

Vitamin B12 deficiency can cause reversible hair color loss in children.

research The association between serum zinc levels and subjective symptoms in zinc deficiency patients with chronic liver disease

January 2020 in “Journal of Clinical Biochemistry and Nutrition”

Low zinc levels in chronic liver disease patients are linked to more severe symptoms like taste issues and skin problems, and zinc supplements might help.