128 citations
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December 2006 in “Journal of Biological Chemistry” Altering SSAT affects fat metabolism and body fat in mice.
128 citations
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August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
24 citations
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May 1985 in “The Journal of Clinical Endocrinology & Metabolism” A circulating inhibitor caused insulin resistance, but clomiphene improved symptoms.
July 2026 in “Plastic and Aesthetic Research” Fat transplantation is becoming important in medicine for repairing tissues and delivering drugs.
January 2018 in “Karger Kompass” Skin symptoms like fragile skin and easy bruising can indicate Cushing's syndrome, which requires early diagnosis and treatment to prevent serious health issues.
4 citations
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January 2021 in “Current Research in Physiology” μ-Crystallin in mouse muscle increases fat metabolism.
31 citations
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July 2012 in “Journal of Lipid Research” ACBP is crucial for healthy skin in mice.
2 citations
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November 2023 in “Skin Appendage Disorders” Lipedematous scalp may have a genetic link and could be associated with psychiatric conditions.
30 citations
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January 2013 in “Obesity Surgery” Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.
17 citations
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September 2017 in “Journal of Cosmetic Dermatology” Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.
March 2026 in “Plastic and Aesthetic Research” Adipose-derived stem cell exosomes can help reduce skin aging from UV exposure.
106 citations
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October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
8 citations
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February 2002 in “Journal of Medical Genetics” Skin changes can indicate a risk for breast cancer.
3 citations
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October 2010 in “Journal of Experimental & Clinical Medicine” Obesity is a major risk factor for insulin resistance in Taiwanese women with PCOS, which is also an independent risk factor for metabolic syndrome.
22 citations
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January 2012 in “Obstetrics and Gynecology International” Obese women with PCOS have more cardiovascular risk factors, and waist-to-stature ratio is a better health marker than waist-to-hip ratio.
May 2026 in “Pharmaceuticals” Incretin-based drugs for obesity often cause gastrointestinal issues, with tirzepatide having the most reports.
5 citations
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December 2004 in “Dermatology” Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
40 citations
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November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
1 citations
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May 2006 in “Thyroid Research and Practice” Skin can become dry and thick in hypothyroidism.
July 2020 in “Endocrine practice” A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.
March 2020 in “International journal of contemporary medical research” Patients with metabolic syndrome often have skin problems like acanthosis nigricans and skin tags, and early treatment is important to prevent serious issues.
4 citations
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January 2016 in “Annals of Dermatology” More severe hair loss links to thicker heart fat, suggesting possible heart disease risk.
18 citations
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August 2012 in “Cutaneous and Ocular Toxicology” People with alopecia areata have higher insulin resistance.
46 citations
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July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
40 citations
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May 2014 in “PLoS ONE” Chronic stress can reduce skin pigmentation.
May 2014 in “The Journal of Alternative and Complementary Medicine” Higher levels of chromium, selenium, and copper in hair are linked to increased insulin resistance in visceral-obese adults.
2 citations
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December 2019 in “Journal of Dermatological Treatment” Metabolic syndrome reduces effectiveness of hair loss treatment.
March 2025 in “Forum Dermatologicum” Metabolic syndrome may worsen certain skin conditions, and managing both together is important.
People with androgenic alopecia are more likely to have metabolic syndrome than healthy individuals.