117 citations
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November 2008 in “Drug Development and Industrial Pharmacy” Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
52 citations
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March 2015 in “Tissue Engineering Part C Methods” 3D images of skin show collagen is evenly spread, but elastic fibers are fewer near hair follicles.
211 citations
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June 2012 The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
September 2022 in “Dermatologic Therapy” 82 citations
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January 1994 in “Skin Pharmacology and Physiology” Hair follicles and glands significantly increase steroid absorption in skin.
20 citations
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August 2014 in “Therapeutic delivery” The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
87 citations
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September 2016 in “Journal of Controlled Release” Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.
5 citations
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March 2024 in “Frontiers in Bioengineering and Biotechnology” A detailed 3D model of human skin was created to help develop artificial skin.
21 citations
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March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
10 citations
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June 2023 in “Preprints.org” Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
3 citations
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September 2024 in “The FASEB Journal” Dermal white adipose tissue helps regulate hair growth, protect skin, and aid wound healing.
39 citations
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April 2012 in “Journal of controlled release” New method uses hair follicles to deliver drugs deep into the skin.
July 2020 in “CRS 2020 Virtual Annual Meeting” Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.
48 citations
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April 2019 in “ACS Applied Materials & Interfaces” A new method for delivering drugs through the skin using biodegradable particles was found to be effective.
September 2018 in “Dermatologic Surgery”
April 2023 in “Journal of Investigative Dermatology” Skin cells and immune cells change in a skin condition called hidradenitis suppurativa, and a certain treatment can improve these changes.
27 citations
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September 2015 in “Drug development and industrial pharmacy” Liposomal adapalene improves delivery to hair follicles and reduces side effects for acne treatment.
January 2015 in “Indo American Journal of Pharmaceutical Research” Mesotherapy uses small injections to improve skin, reduce fat, and treat hair loss effectively and quickly.
19 citations
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October 2020 in “Biomedical Microdevices” Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.
August 2004 in “Journal of the American College of Surgeons” Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.
25 citations
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November 2015 in “Journal of Dermatological Science” Sebum helps protect human skin from microbes.
21 citations
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January 2023 in “Biomaterials Science” Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.
1 citations
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April 2017 in “Journal of Investigative Dermatology” Topical glucocorticoids thin the skin and change collagen structure.
49 citations
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March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
2 citations
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February 2023 in “Anais Brasileiros de Dermatologia”
21 citations
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December 2016 in “European journal of pharmaceutics and biopharmaceutics” Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.
96 citations
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April 2017 in “Oncotarget” Smaller nanoemulsions can penetrate skin and hair follicles better, which may be useful for delivering drugs and vaccines through the skin.
1 citations
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December 2024 in “Tissue Barriers” The epidermis is the stiffest skin layer.
2 citations
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March 1977 in “British Journal of Dermatology” Nandrolone phenylpropionate injections thickened the skin and enlarged oil glands in female hairless hamsters.