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Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

EISA uses enzymes to create precise nanostructures in cells, offering new ways to design adaptive materials and therapies.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

Targeting amphiregulin may improve treatment for fibrosis and cancer.

Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

Reduced matriptase activity causes skin and hair issues in both humans and mice.

DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Isoxazole 9 (ISX9) may help regrow hair by activating certain cell signals.

The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Phytosterols may help manage prostate issues but are less effective than synthetic drugs.

Adding a second method to PROTACs could improve cancer treatment.

Hom Thong banana peels can help reduce skin pigmentation by inhibiting melanin production.

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

Functionalized bacterial cellulose can improve medical tissue engineering.

Osmanthus fragrans var. aurantiacus Makino may help treat inflammation due to its antioxidative and anti-inflammatory properties.

Canagliflozin helps overcome progestin resistance in certain endometrial cancer cells.

Compounds from Ziziphus spina-christi roots show strong antibacterial and antioxidant potential.