198 citations
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March 1999 in “Journal of Investigative Dermatology” Keratin 15 helps maintain tissue integrity and is reduced in activated keratinocytes.
125 citations
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February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
99 citations
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October 2008 in “Journal of Investigative Dermatology” Mutations in the ST14 gene cause skin and hair issues by disrupting important protein processing.
91 citations
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July 2004 in “Journal of Biological Chemistry” Overexpressing SSAT enzyme reduces prostate tumor growth in mice.
90 citations
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December 2008 in “Journal of Investigative Dermatology” Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
90 citations
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February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Interleukin-1 increases keratin K6 production in skin cells.
57 citations
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August 2002 in “American Journal Of Pathology” Cathepsin L deficiency causes hair and skin issues in mice.
56 citations
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November 2003 in “Journal of Investigative Dermatology” MMP-19 may worsen skin diseases by affecting skin growth and inflammation.
53 citations
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January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
40 citations
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January 2022 in “Nutrients” Diet can influence inflammatory skin diseases.
37 citations
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October 2021 in “Journal of Clinical Investigation” Skin inflammation can worsen intestinal inflammation and colitis.
35 citations
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January 2024 in “BioMolecular Concepts” Lifestyle changes, exercise, and antioxidants can help manage polycystic ovary syndrome.
35 citations
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June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
32 citations
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January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
23 citations
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March 2017 in “Journal of Investigative Dermatology” An artificial lipid barrier can restore hair growth in cases of SCD1 deficiency.
21 citations
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November 2019 in “Molecular & Cellular Proteomics” Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.
20 citations
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July 2017 in “Journal of Investigative Dermatology” IL-1 receptor absence in mice leads to skin cysts and changes in immune response after UVB exposure.
16 citations
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March 2024 in “International Journal of Molecular Sciences” Natural compounds and biomimetic engineering can improve wound healing by enhancing fibroblast activity.
15 citations
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November 2024 in “Materials” PHAs are promising biodegradable materials for medical and dental uses.
13 citations
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September 2022 in “Biomolecules” The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.
13 citations
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November 2021 in “Frontiers in Immunology” Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.
9 citations
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June 2022 in “Microorganisms” We need safe, affordable drugs to fight coronaviruses effectively.
6 citations
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October 2023 in “Pharmaceuticals” Eclipta prostrata extract may help with memory and diabetes due to its antioxidant and enzyme-inhibiting properties.
6 citations
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October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
5 citations
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November 2025 in “Cells” Advancements in wound healing aim to improve personalized treatments and enhance healing outcomes.
5 citations
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January 2025 in “Science Advances” 5α-reductase 2 is crucial for stress response in male rats.
5 citations
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May 2021 in “EMBO journal” Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
3 citations
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May 2025 in “Journal of Ovarian Research” m6A deregulation plays a key role in PCOS and could lead to new treatments.
3 citations
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March 2024 in “Viruses” γδ T cells are essential for wound healing after poxvirus infection.
2 citations
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February 2024 in “International Journal of Molecular Sciences” Negative Pressure Wound Therapy speeds up wound healing by reducing inflammation and promoting skin cell growth.