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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

A 7-year-old girl was diagnosed with trichothiodystrophy due to low sulfur levels in her hair.

Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.

The enzyme from human skin can cross-link proteins and needs calcium to work.

Tanning ability is linked to specific DNA changes in skin genes.

Nitrofurantoin may cause sub-acute cutaneous lupus erythematosus.

The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.

SH-SY5Y cell lysate is effective for diagnosing Satoyoshi syndrome.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

Gut bacteria overgrowth may cause some Post-Finasteride Syndrome symptoms.

A rare skin infection in a 10-year-old kidney transplant patient was successfully managed by adjusting medication.

Mice hair follicles take in the amino acid cystine.

IL-1 blockade is effective for treating SURF, and personalized treatment is needed.

A new green method accurately measures finasteride and tadalafil in drugs and plasma.

Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.

A rare gene variant causes sexual development issues in siblings, needing personalized treatment.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.

Duloxetine, escitalopram, and finasteride may be effective against bacteria and fungi.

Using K2S2O8 as an oxidizing agent in a specific condition, we can make Finasteride with 96.3% yield and 99.6% purity. This method is also good for other compounds and is environmentally friendly.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Trichothiodystrophy hair is structurally abnormal with protein and organization issues.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.