research The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
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270-300 / 1000+ resultsresearch 3D Printing—A “Touch-Button” Approach to Manufacture Microneedles for Transdermal Drug Delivery
3D printing can make microneedles for drug delivery faster and cheaper.
research Gene therapy to enhance angiogenesis in chronic wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Progress in Topical and Transdermal Drug Delivery Research—Focus on Nanoformulations
Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.
research Developing a JAK Inhibitor for Targeted Local Delivery: Ruxolitinib Cream
Ruxolitinib cream effectively targets and treats inflammatory skin diseases.
research MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression
MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.
research Pharmacology of Natural Volatiles and Essential Oils in Food, Therapy, and Disease Prophylaxis
Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
research Sex Identification of Feather Color in Geese and the Expression of Melanin in Embryonic Dorsal Skin Feather Follicles
Female goslings have darker feathers than males due to more melanin.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research From Piezoelectric Nanogenerator to Non-Invasive Medical Sensor: A Review
Piezoelectric Nanogenerators are promising for non-invasive health monitoring but need efficiency and durability improvements.
research The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy
PRP therapy shows promise for anti-aging but lacks consistent evidence and standardization.
research Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching
Different ligands change the shape of the TRPV3 ion channel in unique ways.
research Efficient Gene Editing for Heart Disease via ELIP-Based CRISPR Delivery System
ELIP-based CRISPR delivery improves heart disease gene editing but needs more testing.
research Advances in Nanotechnology Research in Food Production, Nutrition, and Health
Nanotechnology can improve food safety, nutrition, and health, but safety and regulation challenges need addressing.
research An update of polycystic ovary syndrome: causes and therapeutics options
Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.
research Orchestration of tissue‐scale mechanics and fate decisions by polarity signalling
Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
research Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway
Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
research Exploring extracellular vesicles as novel therapeutic agents for intervertebral disc degeneration: delivery, applications, and mechanisms
Extracellular vesicles may help prevent and repair spine disc degeneration.
research Regulatory T cells in skin regeneration and wound healing
Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
research Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek
The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.
research South Asian Epidemic of Antifungal Therapeutic Failures: Congress Proceedings and Take-home Messages. First International Congress of SAARCUM: South Asian Alliance against Recalcitrant Cutaneous Mycosis. 17 November 2018, Medanta – The Medicity, Gurugram, India
The congress concluded that misuse of antifungal drugs in South Asia has led to widespread treatment failure, and new approaches and regional cooperation are needed.
research Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids
Cannabidiol shows promise as an effective treatment for acne.
research Long-acting microneedle formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research Impact of Reducing Obesity in PCOS: Methods and Treatment Outcomes
Weight loss improves PCOS symptoms and overall health.
research The Potential Reversible Transition between Stem Cells and Transient-Amplifying Cells: The Limbal Epithelial Stem Cell Perspective
Corneal cells can potentially revert to stem cells, aiding in repair and regeneration.
research An Advanced Review: Polyurethane-Related Dressings for Skin Wound Repair
Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.
research Mechanistic Insights into Plant-Derived Exosomes, Their Cross-Kingdom Effects, and Potential Biomedical Applications in Skin Wounds Repair
Plant-derived exosomes show promise for healing skin wounds but need more research and trials.
research The Genus Astragalus Species as an Emerging Source of Bioactive Phytochemicals: A Review of Dermatological and Cosmetic Applications
Astragalus plants may improve skin health and have anti-aging benefits.
research Recent Advances in Microneedling-Assisted Cosmetic Applications
Microneedling improves skin and hair conditions by enhancing treatment absorption and stimulating growth factors.
research Insulin resistance as risk factor for the development of type 2 diabetes mellitus: a systematic approach
Insulin resistance increases the risk of developing type 2 diabetes and other health issues.