318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
292 citations
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April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
214 citations
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September 2015 in “Stem Cells Translational Medicine” Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
188 citations
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December 2020 in “Foods” Polyphenols in plant foods help prevent diseases and have potential uses in food, cosmetics, and more.
130 citations
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December 2022 in “Antioxidants” Natural polysaccharides have strong antioxidant properties that help fight diseases like Alzheimer's, diabetes, and heart disease.
101 citations
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March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
96 citations
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October 2021 in “Reproductive Sciences” Women with PCOS often experience depression and anxiety, affecting their quality of life.
92 citations
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December 2020 in “Brain Sciences” Indian herbs like Bacopa monnieri and Centella asiatica may help memory, but more research is needed.
90 citations
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October 2023 in “Advanced Drug Delivery Reviews” Controlling inflammation can help heal diabetic foot ulcers.
82 citations
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September 2020 in “Briefings in Bioinformatics” SARS-CoV-2 may worsen IPF due to shared genes and pathways, suggesting potential drug targets.
81 citations
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February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
72 citations
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July 2022 in “Frontiers in Systems Biology” Modern lifestyles harm beneficial microbes, affecting health.
67 citations
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November 2019 in “Molecules” Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
67 citations
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December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
63 citations
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September 2020 in “Frontiers in Microbiology” Probiotics show promise for health benefits but need more research to understand how they work.
63 citations
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January 2010 in “Frontiers in Aging Neuroscience” 3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
61 citations
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April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
61 citations
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January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
59 citations
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July 2023 in “PLoS ONE” Metabolic syndrome is common in African populations, needing urgent prevention and treatment.
59 citations
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August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
54 citations
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March 2024 in “Journal of Medicinal Chemistry” N-oxides are important in medicine for improving drug properties and targeting.
50 citations
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November 2021 in “Viruses” Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.
49 citations
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February 2025 in “Science Advances” Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
48 citations
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January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
47 citations
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September 2022 in “European Heart Journal” Women may need different blood pressure guidelines than men for heart disease prevention.
43 citations
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September 2021 in “Nutrients” Persimmons offer health benefits and can be used in new products and sustainable applications.
40 citations
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November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
39 citations
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November 2021 in “Clinical Endocrinology” Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
38 citations
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January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
37 citations
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October 2021 in “Nutrients” Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.