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Mothers with atopic dermatitis have higher risks of pregnancy complications and their children are more likely to develop certain health conditions.

Pregnancy can cause various skin changes, including pigmentation, acne, and stretch marks, and may affect preexisting skin conditions.

Prenatal THC exposure may harm ovarian health and fertility.

Exposure to certain glycol ethers during pregnancy may be linked to lower verbal comprehension in children.

Inhibiting 5α-reductase during late pregnancy shortens gestation, reduces litter size, and harms memory in rat offspring.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

Methimazole may cause skin defects in babies if taken during pregnancy.

Topiramate impairs gene transmission in zebrafish, while Ginkgo biloba reduces harmful effects of high β-catenin levels.

Hyperandrogenism and insulin resistance in PCOS-like rats can lead to pregnancy complications due to increased cell death in the uterus and placenta.

PCOS increases risks of gestational diabetes, hypertension, and caesarian deliveries in pregnancy.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Mice with a specific BRCA1 mutation have a higher risk of tumors, especially in the uterus and ovaries.

Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

Father's finasteride use may affect son's fertility and testicular function.

Low biotin intake during pregnancy can affect biotin transport in mothers and fetuses.

Wnt-activating drugs generally do not increase cancer risk.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

Mothers and newborns with dental fillings have higher mercury in their hair, but adding fillings during pregnancy doesn't raise mercury levels further.

Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.

Endocrine-disrupting chemicals cause irreversible harm to children's development, increasing disease risk.

Finasteride causes reproductive malformations in male rats.

Control variability makes it hard to confirm low-dose endocrine effects.

The commentary stresses the importance of using historical control data and proper interpretation in evaluating developmental toxicity.