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The commentary stresses the importance of using historical control data and proper interpretation in evaluating developmental toxicity.

During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.

Finasteride use in male rats may harm their male offspring's liver function.

Most pregnant women experience skin changes, mainly increased pigmentation, and some develop pregnancy-related skin conditions and infections.

Mothers and newborns with dental fillings had higher mercury in their hair, but getting fillings during pregnancy didn't raise mercury levels further.

Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

Low-dose methotrexate is generally safe but can cause mild to severe side effects, and folic acid can reduce these risks.

Pregnancy-related skin disorders need accurate diagnosis and treatment to prevent risks to the baby.

Finasteride and DEHP exposure during development can change reproductive markers in rats.

Fetal exposure to diazoxide can cause hair loss and abnormal hair growth in infants.

Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.

Titanium dioxide nanoparticles may harm the male reproductive system.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Lithium can cause some health issues, but severe risks are low.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Obesity negatively affects the endometrium, leading to higher miscarriage risk and impaired cell function.

High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.

Pregnancy can cause skin changes and may affect pre-existing skin conditions, with some treatments not safe for use during pregnancy.

Ets2 gene is crucial for placental development in mice.

Pre-natal, internal, and external factors may contribute to the development of Autism Spectrum Disorder (ASD).

HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.

HIV-positive pregnant women are more likely to experience severe bleeding, and a pregnant woman with familial hypertriglyceridemia had a successful early delivery with special care.

Pregnant women with isolated hypothyroxinemia face more health issues, so iodine and folic acid supplements are important before and during early pregnancy.

Maternal exposure to artificial food coloring may increase skin disease risk in rat offspring.

Testosterone's health effects are complex and not definitively understood.

NIPT can help detect potential maternal cancer, and GIPXplore can identify immune diseases in pregnancies.

Exposure to low doses of finasteride in the womb causes changes in the prostate of both male and female gerbils.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.