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Certain maturity signs appear before and after the first release of sperm in boys.

A rare case of isolated trichothiodystrophy was identified, marked by brittle hair with low sulfur content.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Testosterone therapy had limited benefits for a man with depression and suspected low testosterone, highlighting the need for careful diagnosis and treatment planning.

A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.

Transgender and gender diverse youth often have skin issues like acne and scarring, but few get referred to dermatologists.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Testosterone therapy in transgender men can cause acne.

A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.

Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.

Finasteride for hair loss can cause erectile dysfunction due to tissue fibrosis.

Ovarian steroid cell tumors can mimic adrenal hyperplasia, and surgery can normalize hormone levels.

Hair wrapped tightly around a boy's penis can cause serious damage if not treated quickly.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.

A new genetic variant causes trichothiodystrophy in two brothers, but their mother may carry it without showing symptoms.

Tay syndrome is a unique genetic disorder causing skin, hair, and developmental issues.

Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.

Androgenetic alopecia is more common in men, linked to genetics and androgen levels, but routine pelvic ultrasound isn't recommended.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Local testosterone treatment improved sexual desire in a female with fragile X syndrome.

Steroid treatment greatly improved the symptoms of a boy with a rare disorder called Satoyoshi syndrome.

Men with isolated hypogonadotropic hypogonadism have partial steroid deficiencies, while those with panhypopituitarism have severe deficiencies.

A rare ovarian tumor caused hair loss in a post-menopausal woman, which almost completely stopped after surgery.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.