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Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Type 2 immunity helps control mite growth in hair follicles, preventing damage.

Brepocitinib effectively reduces inflammation and improves symptoms in cicatricial alopecia with good safety.

A JAK inhibitor improved both severe hair loss and chronic skin disease in one patient.

Thyroid and skin autoimmune diseases share genetic and immune links, affecting both tissues.

Chronic skin diseases and metabolic syndrome are linked by shared inflammation pathways.

Bifidobacterium animalis subsp. lactis J12 helps reduce atopic dermatitis symptoms.

Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.

A plant-based diet and certain probiotics may improve skin health and reduce inflammation.

Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.

Ritlecitinib helps reduce inflammation and promote hair regrowth in alopecia areata, especially in patchy-type cases.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Higher levels of certain proteins in the blood are linked to more severe patchy alopecia areata.

Metabolic syndrome is linked to skin diseases, requiring integrated treatment and monitoring.

Balancing good and harmful microbes is key to healing chronic wounds.

Aging skin causes inflammation that affects the whole body.

Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.

Lifestyle changes, exercise, and antioxidants can help manage polycystic ovary syndrome.

Granzyme B is important in autoimmune skin diseases and could be a new treatment target.

Ruxolitinib cream effectively targets and treats inflammatory skin diseases.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.

Dermal white adipose tissue helps regulate hair growth, protect skin, and aid wound healing.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.

Pediatric alopecia areata is more immune-active than adult cases, suggesting age-specific treatments and potential use of JAK inhibitors.

Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.

Understanding how skin cells react to pressure can help diagnose and manage pressure-related skin disorders.