3 citations
,
January 2011 in “International journal of trichology” Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.
April 2017 in “Journal of Investigative Dermatology” HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
38 citations
,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
5 citations
,
January 1993 in “Hormone and Metabolic Research” DHEA and DHEA-S help maintain underarm hair in older women.
1 citations
,
January 2025 in “Pediatria i Medycyna Rodzinna” Accurate diagnosis and zinc supplements can improve life quality in acrodermatitis enteropathica, even with normal zinc levels.
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.
2 citations
,
December 2023 in “International journal of molecular sciences” Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
51 citations
,
March 2019 in “Experimental Dermatology” Matrix changes and increased MMPs contribute to skin inflammation in hidradenitis suppurativa.
May 2025 in “Journal of Dermatological Treatment” The shampoo improved seborrheic dermatitis symptoms, but worked better for males than females.
13 citations
,
September 2011 in “Archives of dermatology” A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.
1 citations
,
July 2025 in “Journal of Human Immunity” Minoxidil helps restore thymus size in 22q11.2 deletion syndrome.
3 citations
,
April 2022 in “Research Square (Research Square)” PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
3 citations
,
August 2010 in “Letters in Drug Design & Discovery”
70 citations
,
March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
37 citations
,
February 2023 in “Gut Microbes” Gut bacteria can lower androgen levels in male mice.
20 citations
,
August 1960 in “PubMed” Selenium sulfide may affect hair root health.
5 citations
,
September 2021 in “Journal of Medical Biochemistry” wAMD patients have higher oxidative stress, suggesting antioxidant treatment may help.
8 citations
,
February 2025 in “Cell Systems” Engineered bacteria can deliver antioxidants to protect skin.
IL-18 signaling helps mature Tregs move into the thymus.
Selenium is essential but can be harmful in excess, and China struggles with balancing its levels for health.
December 2010 in “OhioLink ETD Center (Ohio Library and Information Network)” Sry may regulate fatty acid metabolism and shows different expression levels in rat tissues.
4 citations
,
January 1989 in “Journal of Steroid Biochemistry” Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
3 citations
,
June 2025 in “Journal of Cellular and Molecular Medicine” CuATSM speeds up wound healing and reduces scarring.
1 citations
,
October 2025 in “EBioMedicine” Women have a higher DHT/testosterone ratio than men, possibly due to gut bacteria activity.
43 citations
,
July 1994 in “Journal of Cell Science” Cross-linked proteins help maintain the structure of hair, feathers, and hagfish teeth.
15 citations
,
June 2011 in “Journal of Investigative Dermatology” Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.
105 citations
,
February 2010 in “Endocrinology” The skin produces and responds to thyroid-stimulating hormone, which is controlled by other thyroid-related hormones.
24 citations
,
November 2015 in “Experimental Cell Research” Sebum from sebocytes is important for skin health and linked to conditions like acne and hair loss.
19 citations
,
March 2016 in “Frontiers in Plant Science” Spermidine is essential for plant growth and adaptation to stress.