research 918 Tissue engineered human hair follicles from genetically, environmentally and extrinsically reprogrammed dermal papilla cells
Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
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research In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research Pemphigus Foliaceus in a 26-year-old Hackney Pony
The pony's skin condition improved significantly with prednisolone treatment.
research Rekindling the lost hair‐forming world
Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
research Getting to the Core of the Dermal Papilla
The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
research The germinative epithelium of sheep vibrissae and wool follicles has extensive proliferative potential but is dependent on the dermal papilla
Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
research Morphological and functional analysis on M3R mediated sweating in TSC1 k/o mouse
Sox13 is a marker for early hair follicle development but not essential for skin and hair growth.
research Alopecia in IL-10-deficient mouse pups is c-kit-dependent and can be triggered by iron deficiency
Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
research Characterization of human dermal sheath cells reveals CD36-expressing perivascular cells associated with capillary blood vessel formation in hair follicles
CD36-expressing dermal sheath cells help form blood vessels in hair follicles, aiding hair growth.
research Joint Public Review: TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 is crucial for hair growth and regeneration, and boosting it can help prevent hair loss.
research Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging
Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
research Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1–Dependent Manner
Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
research Gynecomastia and Premature Thelarche
Gynecomastia and premature thelarche often resolve naturally but need evaluation to rule out serious issues.
research The Double-Edged Proteins in Cancer Proteomes and the Generation of Induced Tumor-Suppressing Cells (iTSCs)
Tumor proteins can both promote and suppress cancer, depending on the situation.
research TAZ enhances the activity of the AKT signaling pathway to promote adipogenesis of gADSCs
TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.
research Vitamin-D3 modulates human hair follicle epithelial progenitor cells in situ and in vitro
research Pathogenesis of graft-versus-host-disease
Graft-versus-host disease occurs when donor immune cells attack the recipient's body, causing skin, gut, and liver damage.
research Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages
The skin can still regenerate and function well even with fewer fibroblasts.
research 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Expression of steroidogenic enzymes in human sebaceous glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research SOX9 in organogenesis: shared and unique transcriptional functions
SOX9 is essential for the development of various organs and hair follicles.
research 837 Characterization of cutaneous hormone production through analysis of skin secretions
Skin produces different hormones depending on body part and sex, and a new method can measure them.
research Tissue engineering of human hair follicles using a biomimetic developmental approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling
SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
research In vitro mesenchymal–epithelial interaction facilitates de novo hair follicle formation
Adult skin cells can be used to create new hair in a lab.
research Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice
Overexpressing IGF-1 in mice leads to skin abnormalities and tumors.
research Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease.
Fibroblast and immune cell interactions affect tissue repair and fibrosis.