Reviewers criticized the study's methods and suggested focusing on drug mechanisms instead of repositioning due to social media data quality concerns.
Reviewers suggested the study on finding new drug uses through social media side-effects needs better methods and clearer limitations.
The study improved and was accepted despite initial concerns about data clarity, methodology, and potential overfitting.
The peer review highlighted the need for clearer data handling, questioned the study's validity, and recognized improvements from the original version.
Reviewers criticized the study for its assumptions, social media data collection issues, and lack of comparison to existing methods.
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,
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,
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,
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,
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,
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,
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,
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,
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,
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,
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,
January 2022 in “Stem cell biology and regenerative medicine” New methods to test hair growth treatments have been developed.
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December 2025 in “Brazilian Journal of Chemical Engineering” October 2025 in “Pharmaceuticals” Auranofin shows promise as a cancer treatment, especially when combined with other therapies.