November 2021 in “International Journal of Trichology” Low PON1 levels may indicate and predict the severity of hair loss.
4 citations
,
February 2018 in “Journal of Investigative Dermatology” The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.
2 citations
,
May 2022 in “Diagnostics” Vitamin D levels in hair don't match those in blood, so hair isn't a reliable indicator of Vitamin D status.
November 2025 in “European Journal of Endocrinology” Hair steroid profiling is a feasible, non-invasive alternative to serum analysis for assessing hormone levels and metabolism.
17 citations
,
June 2023 in “Pharmaceuticals” Inflammasome proteins may help diagnose and treat Parkinson's disease.
119 citations
,
November 2016 in “American journal of human genetics” Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
100 citations
,
May 2006 in “American Journal Of Pathology” Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
92 citations
,
September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
84 citations
,
September 2008 in “Developmental biology” Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
70 citations
,
August 2006 in “Cancer Research” AP-1 controls tumor cell type by affecting key signaling pathways.
59 citations
,
July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
58 citations
,
February 2013 in “Journal of Biological Chemistry” LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.
38 citations
,
July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.
28 citations
,
January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
26 citations
,
September 2013 in “Journal of Dermatological Science” Serum granulysin levels can indicate the activity and prognosis of alopecia areata.
20 citations
,
November 2019 in “Stem Cells” Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
16 citations
,
May 1982 in “Postgraduate Medical Journal” Minoxidil can cause pericardial and pleural effusions with high protein content.
15 citations
,
January 2018 in “Indian Journal of Dermatology” Women with androgenetic alopecia have lower zinc and iron levels.
14 citations
,
March 2015 in “Stem Cell Research & Therapy” ABCG2 protein marks stem-like skin cells in human epidermis.
12 citations
,
August 2018 in “BMC Biotechnology” A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.
8 citations
,
July 2022 in “Metabolites” Higher uric acid levels are linked to fewer urinary symptoms in healthy Korean men.
7 citations
,
January 2019 in “PeerJ” A protein called sFRP4 can slow down hair regrowth.
6 citations
,
November 2021 in “Oncology Research and Treatment” Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.
5 citations
,
December 2021 in “Scientific Reports” Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.
4 citations
,
July 2020 in “Biochemical and Biophysical Research Communications” A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.
3 citations
,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
3 citations
,
April 2022 in “Biomolecules” Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.
1 citations
,
April 2024 in “Metabolites” Activated protein C helps protect mice from long-term radiation damage.
1 citations
,
January 2020 in “PubMed” Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.