research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
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research Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Non-invasive assessment of hair regeneration in androgenetic alopecia mice in vivo using two-photon and second harmonic generation imaging
New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.
research An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing ‘the Big Eight Strikes’
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
research The Potential Utility of Tirzepatide for the Management of Polycystic Ovary Syndrome
Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.
research Sex-Related Differences in the Pharmacological Response in SARS-CoV-2 Infection, Dyslipidemia, and Diabetes Mellitus: A Narrative Review
Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.
research The Non-Cosmetic Dermatological Use of Botulinum Neurotoxin
Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.
research Subject Index
research Minoxidil
research Canadian Expert Recommendations on Safety Overview and Toxicity Management Strategies for Sacituzumab Govitecan Based on Use in Metastatic Triple-Negative Breast Cancer
Sacituzumab Govitecan is effective for certain breast cancers but requires careful management of side effects.
research Establishing an Evidence-Based System for Cosmetic Safety and Efficacy Evaluation
A comprehensive system is needed to ensure cosmetics are safe and effective, using global insights and new AI technologies.
research Ethanol extract of the freshwater green alga Prasiola japonica attenuates hair loss and promotes hair growth in a testosterone-induced hair loss model
Prasiola japonica extract may help reduce hair loss and promote hair growth.
research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.
research Hirsutism-A Comprehensive Update of Embryology, Aetiopathogenesis and Therapeutic Approach
The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
research Activation of mitochondrial aldehyde dehydrogenase 2 promotes hair growth in human hair follicles
Activating ALDH2 can boost hair growth.
research Exhaustive analysis of scalp hair regression: subjective and objective perception from initial hair loss to severe miniaturisation and drug-induced regrowth
Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
research The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells
SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.
research Wnt target gene Ascl4 is dispensable for skin appendage development
The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
research Intermittent nitrate transdermal therapy
Using minoxidil for hair growth may cause skin lesions in some people, and taking breaks from nitrate patches for angina might worsen symptoms.
research Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.
research Convergent Decay of Skin-specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research Aromatase deficiency in a male patient - Case report and review of the literature.
A male with aromatase deficiency improved bone health with estradiol treatment.
research Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea
The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
research The effects of oestrogens on linear bone growth
Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
research HR Gene Variants Identified in Mexican Patients with Alopecia Areata
A specific gene variant may increase the risk of developing Alopecia Areata.
research Idiopathic Hirsutism*
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research Molecular basis of androgen action on human sexual desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
research UPDATE ON IDIOPATHIC HIRSUTISM: DIAGNOSIS AND TREATMENT
The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.