research Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter’s Methylation in AFAB People
Testosterone treatment may change estrogen receptor methylation in AFAB individuals.
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330-360 / 1000+ resultsresearch A Gender Hypothesis of sex disparities in adverse drug events
Gendered social factors, not just biology, contribute to sex differences in adverse drug events.
research Minoxidil-induced hypertrichosis: Pathophysiology, clinical implications, and therapeutic strategies
Minoxidil can cause unwanted hair growth, so personalized care and support are important.
research Menstrual Disorders
The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.
research The connection of 5-alpha reductase inhibitors to the development of depression
5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
research No Increased Cardiovascular Hazard with Oral 5-Alpha-Reductase Inhibitors in Treatment of Androgenetic Alopecia: A TriNetX Retrospective Cohort Study
Oral 5-alpha-reductase inhibitors for hair loss don't increase heart risk.
research Early androgenetic alopecia as a possible indicator of diabetes mellitus and its link to cardiovascular risks: a cross-sectional study
Early hair loss may indicate a higher risk of diabetes in young and middle-aged adults.
research Head and Neck Restoration in Scar Alopecia: Hair Transplantation in Scalp, Eyebrows, Beard and Mustache
Hair transplantation is effective for treating scar-related hair loss on the head and neck.
research Comparison of Therapeutic Efficacy of Topical Tacrolimus 0.1% and Topical Dithranol 0.5% in Treatment of Alopecia Areata
Dithranol is more effective than Tacrolimus for hair regrowth in alopecia areata.
research Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism
Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
research Expression of Desmoglein 1 Compensates for Genetic Loss of Desmoglein 3 in Keratinocyte Adhesion
Desmoglein 1 can partly make up for the loss of Desmoglein 3 in hair adhesion but not in mucous membranes.
research Thymic Stromal Lymphopoietin in Cutaneous Immune-Mediated Diseases
A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
research Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing
Dock5 is important for skin healing and could help treat diabetic wounds.
research Increased plasma renin by vasodilators promotes the progression of abdominal aortic aneurysm
Vasodilators may worsen abdominal aortic aneurysm.
research A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders
The new model helps understand and develop treatments for genetic skin disorders like AEC.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research An induced pluripotent stem cell-based approach for hair follicle development and regeneration
iPSCs show promise for hair regeneration but need more research to improve reliability and effectiveness.
research Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
The mouse model showed defects in adult stem cell maintenance related to Hutchinson-Gilford progeria syndrome.
research Follicular unit extraction [FUE] – One procedure, many uses
FUE is a versatile hair transplant technique with many uses and good outcomes when performed with skill.
research Persistent Gynecomastia due to Short-term Low-dose Finasteride for Androgenetic Alopecia
A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.
research Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes
Females have stronger immune responses to COVID-19 than males, leading to better outcomes.
research Hypertension: sex-related differences in drug treatment, prevalence and blood pressure control in primary care
Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.
research Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia
People with androgenetic alopecia have a higher risk of metabolic syndrome.
research Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity
New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
research Oral Minoxidil for Alopecia Treatment: Risks, Benefits, and Recommendations
Low-dose oral minoxidil can effectively promote hair growth but requires careful monitoring for safety.
research Characterization and Management of Adverse Events of Low-Dose Oral Minoxidil Treatment for Alopecia: A Narrative Review
Low-dose oral minoxidil effectively treats alopecia but can cause side effects like excess hair growth and fluid retention.
research Wokeness in Our Practice
Dermatologists should address discrimination and consider ethnic and gender differences in treatments.
research JAMA Dermatology—The Year in Review, 2021
In 2021, JAMA Dermatology published significant findings on skin conditions post-COVID vaccination, melanoma surveillance, atopic dermatitis treatments, and confirmed that sun protection does not harm bone health.
research Type XVII collagen coordinates proliferation in the interfollicular epidermis
Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
research Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease
The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.