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Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.

Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.

Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.

Hair organoids are effective for testing hair loss treatments.

The risk of skin tumors becoming malignant depends on the specific skin cell type affected.

TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.

Overexpressing IGF-1 in mice leads to skin abnormalities and tumors.

Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.

The keratin 19 promoter effectively targets genes in specific epithelial cells in mice.

Abnormal keratin expression in mice causes severe oral issues, affecting feeding.

Keratinocyte growth factor significantly alters skin and tissue development.

Blocking EGFR in mice causes hair loss and skin changes.

The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

Deleting TNFα gene reduces skin cancer risk in certain mice.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Overexpressing NSD3 in mice causes breast cancer-like tumors and gland abnormalities.

Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.

The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.

Pregnancy-related hormone changes affect Y1 receptor gene expression in mice.

Removing certain hair follicle stem cells worsens skin reactions to allergens.

Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.

Acute stress increases Y1 receptor gene expression in certain brain areas, but repeated stress does not.

Stopping alcohol after long-term use causes anxiety and changes brain chemicals.