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research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth

101 citations , March 2019 in “Cell Stem Cell”

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function

research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching (FRAP) Is an Integrated Measure of Receptor Function

31 citations , July 2004 in “Molecular Medicine”

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

research The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth

17 citations , May 2011 in “Gene Therapy”

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

Additional File 12 of Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus

research Additional file 12 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus

January 2022 in “Figshare”

Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.

Regulatory T Cells Influence Hair Follicle Cycle and Stem Cell Activation

research Keep your hair on

1 citations , June 2017 in “Nature Reviews Immunology”

Immune cells called Treg cells are essential for hair growth and regeneration.

research Testosterone Down-regulates Expression of αVβ3-integrin, E-cadherin and Mucin-1 during Uterine Receptivity Period in Rats

5 citations , October 2018 in “Sains Malaysiana”

Testosterone reduces key molecules needed for early pregnancy in rats.

research Visual Vignette

2 citations , March 2003 in “Endocrine Practice”

The woman's symptoms and tests suggest her adrenal glands are producing too many male hormones.

research Dermal Papilla Cells from Human Hair Follicles Express mRNA for Retinoic Acid Receptors in Culture

9 citations , December 1991 in “Annals of the New York Academy of Sciences”

research A frameshift mutation in HTRA1 expands CARASIL syndrome and peripheral small arterial disease to the Chinese population

21 citations , March 2015 in “Neurological Sciences”

A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.

Androgen Receptor Transactivity Is Potentiated by TGF-β1 Through Smad3 but Checked by Its Coactivator Hic-5/ARA55 in Balding Dermal Papilla Cells

research Androgen receptor transactivity is potentiated by TGF-β1 through Smad3 but checked by its coactivator Hic-5/ARA55 in balding dermal papilla cells

19 citations , September 2011 in “Journal of Dermatological Science”

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

research Integrative Comparison of the Role of the PHOSPHATE RESPONSE1 Subfamily in Phosphate Signaling and Homeostasis in Rice

216 citations , June 2015 in “PLANT PHYSIOLOGY”

OsPHR3 can help breed rice that efficiently uses phosphate without growth issues.

Treatment of Alopecia Areata in Mice by Stimulating Hair Follicles Using Parathyroid Hormone Agonists Linked to a Collagen Binding Domain

research Treatment of Alopecia Areata in Mice by Stimulating the Hair Follicles Using Parathyroid Hormone Agonists Linked to a Collagen Binding Domain

January 2015 in “Journal of clinical & experimental dermatology research”

A protein combining parathyroid hormone and collagen helped hair regrow in mice with a hair loss condition.

research Alopecia Areata: Pituitary Function Assessed by Assay of Pituitary Gonadotropin in Urine11From the Section of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota. The Mayo Foundation, Rochester, Minnesota, is a part of the Graduate School of the University of Minnesota.

4 citations , May 1958 in “Journal of Investigative Dermatology”

research Effects of recombinant human keratinocyte growth factor-2 on hair regeneration in experimental bald rats

January 2012

rhKGF2 significantly promotes hair growth and follicle development.

research Society for Endocrinology guidelines for testosterone replacement therapy in male hypogonadism

39 citations , November 2021 in “Clinical Endocrinology”

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

research Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition

April 2024 in “Communications biology”

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

research Expression and localization of Artemis serine 516 phosphorylation in human scalp skin

5 citations , August 2012 in “Experimental Dermatology”

Artemis phosphorylation at Ser516 may help regulate skin and hair structures.

research Skin-infiltrating CD4+ lymphoma cells depend on hair follicle-derived IL-7

September 2016 in “Journal of Dermatological Science”

Hair follicles produce IL-7, which is essential for certain skin lymphoma cells to survive.

research Melanocortin receptors in fibroblastic cell types of the skin –in vitro and in vivo expression and functional relevance

1 citations , September 2004 in “Experimental Dermatology”

MC-1R is present in skin cells and may help reduce inflammation.

research Cloning and Expression of Cellular Retinoic Acid Binding Protein I Gene in Inner Mongolian Cashmere Goats

1 citations , January 2012

The CRABP I gene in cashmere goats is highly conserved but has unique features at specific amino sites.

research The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia

15 citations , January 2015 in “Skin Pharmacology and Physiology”

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

research Faculty Opinions recommendation of Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.

August 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.

Cachexia and Graft-Versus-Host Disease-Type Skin Changes in Keratin Promoter-Driven TNF Alpha Transgenic Mice

research Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice.

150 citations , August 1992 in “Genes & Development”

TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.

research Einfluss von HRT auf Haut und Haare

1 citations , November 2009 in “Gynäkologische Endokrinologie”

research The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis

127 citations , January 2008 in “PloS one”

Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.

research 033 IL-15 is an unexpected guardian of hair follicle immune privilege and promotes human hair growth ex vivo

April 2021 in “Journal of Investigative Dermatology”

IL-15 helps protect hair follicles from immune attacks and encourages hair growth.

research A pair of transmembrane receptors essential for the retention and pigmentation of hair

11 citations , May 2012 in “Genesis”

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

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